RNA-Guided CRISPR-Cas9 System-Mediated Engineering of Acute Myeloid Leukemia Mutations

by Oliver Brabetz, Vijay Alla, Linus Angenendt, Christoph Schliemann, Wolfgang E. Berdel, Maria-Francisca Arteaga, Jan-Henrik Mikesch
Published 2017-03-01

Future Options of Molecular-Targeted Therapy in Small Cell Lung Cancer

by Arik Bernard Schulze, Georg Evers, Andrea Kerkhoff, Michael Mohr, Christoph Schliemann, Wolfgang E. Berdel, Lars Henning Schmidt
Published 2019-05-01

Weekly screening supports terminating nosocomial transmissions of vancomycin-resistant enterococci on an oncologic ward – a retrospective analysis

by Stefanie Kampmeier, Dennis Knaack, Annelene Kossow, Stefanie Willems, Christoph Schliemann, Wolfgang E. Berdel, Frank Kipp, Alexander Mellmann
Published 2017-05-01

Animal Safety, Toxicology, and Pharmacokinetic Studies According to te ICH S9 Guideline for a Novel Fusion Protein tTF-NGR Targeting Procoagulatory Activity into Tumor Vasculature:...

by Wolfgang E. Berdel, Saliha Harrach, Caroline Brand, Kathrin Brömmel, Andrew F. Berdel, Heike Hintelmann, Christoph Schliemann, Christian Schwöppe
Published 2020-11-01

Somatic Functional Deletions of Upstream Open Reading Frame-Associated Initiation and Termination Codons in Human Cancer

by Lara Jürgens, Felix Manske, Elvira Hubert, Tabea Kischka, Lea Flötotto, Oliver Klaas, Victoria Shabardina, Christoph Schliemann, Wojciech Makalowski, Klaus Wethmar
Published 2021-05-01

Perioperative chemotherapy in gastroesophageal cancer. A retrospective monocenter evaluation of 42 cases.

by Ann-Christin E Brehler, Wolfgang Hartmann, Stefanie Wiebe, Andrea Kerkhoff, Christoph Schliemann, Daniel Palmes, Norbert Senninger, Frank Lenze, Hansjoerg Ullerich, Wolfgang E Berdel, Torsten Kessler
Published 2015-01-01

Radiation synergizes with antitumor activity of CD13-targeted tissue factor in a HT1080 xenograft model of human soft tissue sarcoma.

by Caroline Brand, Burkhard Greve, Tobias Bölling, Hans T Eich, Normann Willich, Saliha Harrach, Heike Hintelmann, Georg Lenz, Rolf M Mesters, Torsten Kessler, Christoph Schliemann, Wolfgang E Berdel, Christian Schwöppe
Published 2020-01-01

Targeting Tissue Factor to Tumor Vasculature to Induce Tumor Infarction

by Andrew F. Berdel, Christian Schwöppe, Caroline Brand, Saliha Harrach, Kathrin Brömmel, Heike Hintelmann, Georg Lenz, Ruediger Liersch, Hauke Heinzow, Christoph Schliemann, Rolf M. Mesters, Wolfgang E. Berdel, Torsten Kessler
Published 2021-06-01

Thoracic Malignancies and Pulmonary Nodules in Patients under Evaluation for Transcatheter Aortic Valve Implantation (TAVI): Incidence, Follow Up and Possible Impact on Treatment D...

by Lars Henning Schmidt, Benedikt Vietmeier, Gerrit Kaleschke, Christoph Schülke, Dennis Görlich, Christoph Schliemann, Torsten Kessler, Arik Bernard Schulze, Boris Buerke, Andreas Kuemmel, Michael Thrull, Rainer Wiewrodt, Helmut Baumgartner, Wolfgang E Berdel, Michael Mohr
Published 2016-01-01

A Phase I Dose Escalation Study of the Triple Angiokinase Inhibitor Nintedanib Combined with Low-Dose Cytarabine in Elderly Patients with Acute Myeloid Leukemia.

by Christoph Schliemann, Joachim Gerss, Stefanie Wiebe, Jan-Henrik Mikesch, Nicola Knoblauch, Tim Sauer, Linus Angenendt, Tobias Kewitz, Marc Urban, Trude Butterfass-Bahloul, Sabine Edemir, Kerstin Vehring, Carsten Müller-Tidow, Wolfgang E Berdel, Utz Krug
Published 2016-01-01

PD-1 and PD-L1 Expression in NSCLC Indicate a Favorable Prognosis in Defined Subgroups.

by Lars Henning Schmidt, Andreas Kümmel, Dennis Görlich, Michael Mohr, Sebastian Bröckling, Jan Henrik Mikesch, Inga Grünewald, Alessandro Marra, Anne M Schultheis, Eva Wardelmann, Carsten Müller-Tidow, Tilmann Spieker, Christoph Schliemann, Wolfgang E Berdel, Rainer Wiewrodt, Wolfgang Hartmann
Published 2015-01-01

Adjuvant chemotherapy-Radiotherapy-Chemotherapy sandwich protocol in resectable soft tissue sarcoma: An updated single-center analysis of 104 cases.

by Christoph Schliemann, Andrea Kerkhoff, Paula Hesse, Sebastian Bröckling, Jendrik Hardes, Arne Streitbürger, Dimosthenis Andreou, Georg Gosheger, Sandra Elges, Eva Wardelmann, Wolfgang Hartmann, Rolf Mesters, Georg Lenz, Normann Willich, Jan Kriz, Hans Eich, Wolfgang E Berdel, Torsten Kessler
Published 2018-01-01

Correction: Potential therapeutic impact of CD13 expression in non-small cell lung cancer.

by Lars Henning Schmidt, Caroline Brand, Janine Stucke-Ring, Christoph Schliemann, Torsten Kessler, Saliha Harrach, Michael Mohr, Dennis Görlich, Alessandro Marra, Ludger Hillejan, Carsten Müller-Tidow, Georg Lenz, Eva Wardelmann, Rainer Wiewrodt, Wolfgang E Berdel, Christian Schwöppe, Wolfgang Hartmann
Published 2017-01-01

Potential therapeutic impact of CD13 expression in non-small cell lung cancer.

by Lars Henning Schmidt, Caroline Brand, Janine Stucke-Ring, Christoph Schliemann, Torsten Kessler, Saliha Harrach, Michael Mohr, Dennis Görlich, Alessandro Marra, Ludger Hillejan, Carsten Müller-Tidow, Georg Lenz, Eva Wardelmann, Rainer Wiewrodt, Wolfgang E Berdel, Christian Schwöppe, Wolfgang Hartmann
Published 2017-01-01

Prostate specific membrane antigen (PSMA) expression in non-small cell lung cancer.

by Lars Henning Schmidt, Birthe Heitkötter, Arik B Schulze, Christoph Schliemann, Konrad Steinestel, Marcel Trautmann, Alessandro Marra, Ludger Hillejan, Michael Mohr, Georg Evers, Eva Wardelmann, Kambiz Rahbar, Dennis Görlich, Georg Lenz, Wolfgang E Berdel, Wolfgang Hartmann, Rainer Wiewrodt, Sebastian Huss
Published 2017-01-01

Aminopeptidase N (CD13): Expression, Prognostic Impact, and Use as Therapeutic Target for Tissue Factor Induced Tumor Vascular Infarction in Soft Tissue Sarcoma

by Torsten Kessler, Ariane Baumeier, Caroline Brand, Michael Grau, Linus Angenendt, Saliha Harrach, Ursula Stalmann, Lars Henning Schmidt, Georg Gosheger, Jendrik Hardes, Dimosthenis Andreou, Johannes Dreischalück, Georg Lenz, Eva Wardelmann, Rolf M. Mesters, Christian Schwöppe, Wolfgang E. Berdel, Wolfgang Hartmann, Christoph Schliemann
Published 2018-12-01

Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML

by Thomas Oellerich, Constanze Schneider, Dominique Thomas, Kirsten M. Knecht, Olga Buzovetsky, Lars Kaderali, Christoph Schliemann, Hanibal Bohnenberger, Linus Angenendt, Wolfgang Hartmann, Eva Wardelmann, Tamara Rothenburger, Sebastian Mohr, Sebastian Scheich, Federico Comoglio, Anne Wilke, Philipp Ströbel, Hubert Serve, Martin Michaelis, Nerea Ferreirós, Gerd Geisslinger, Yong Xiong, Oliver T. Keppler, Jindrich Cinatl
Published 2019-08-01

Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells

by Clément Larrue, Nathan Guiraud, Pierre-Luc Mouchel, Marine Dubois, Thomas Farge, Mathilde Gotanègre, Claudie Bosc, Estelle Saland, Marie-Laure Nicolau-Travers, Marie Sabatier, Nizar Serhan, Ambrine Sahal, Emeline Boet, Sarah Mouche, Quentin Heydt, Nesrine Aroua, Lucille Stuani, Tony Kaoma, Linus Angenendt, Jan-Henrik Mikesch, Christoph Schliemann, François Vergez, Jérôme Tamburini, Christian Récher, Jean-Emmanuel Sarry
Published 2021-01-01

First-In-Class CD13-Targeted Tissue Factor tTF-NGR in Patients with Recurrent or Refractory Malignant Tumors: Results of a Phase I Dose-Escalation Study

by Christoph Schliemann, Mirjam Gerwing, Hauke Heinzow, Saliha Harrach, Christian Schwöppe, Moritz Wildgruber, Anna A. Hansmeier, Linus Angenendt, Andrew F. Berdel, Ursula Stalmann, Björna Berning, Karsten Kratz-Albers, Kristina Middelberg-Bisping, Stefanie Wiebe, Jörn Albring, Christian Wilms, Wolfgang Hartmann, Eva Wardelmann, Tobias Krähling, Walter Heindel, Joachim Gerss, Eike Bormann, Hartmut Schmidt, Georg Lenz, Torsten Kessler, Rolf M. Mesters, Wolfgang E. Berdel
Published 2020-06-01

Loss-of-Function Mutations of <i>BCOR</i> Are an Independent Marker of Adverse Outcomes in Intensively Treated Patients with Acute Myeloid Leukemia

by Jan-Niklas Eckardt, Sebastian Stasik, Michael Kramer, Christoph Röllig, Alwin Krämer, Sebastian Scholl, Andreas Hochhaus, Martina Crysandt, Tim H. Brümmendorf, Ralph Naumann, Björn Steffen, Volker Kunzmann, Hermann Einsele, Markus Schaich, Andreas Burchert, Andreas Neubauer, Kerstin Schäfer-Eckart, Christoph Schliemann, Stefan W. Krause, Regina Herbst, Mathias Hänel, Norbert Frickhofen, Richard Noppeney, Ulrich Kaiser, Claudia D. Baldus, Martin Kaufmann, Zdenek Rácil, Uwe Platzbecker, Wolfgang E. Berdel, Jiří Mayer, Hubert Serve, Carsten Müller-Tidow, Gerhard Ehninger, Friedrich Stölzel, Frank Kroschinsky, Johannes Schetelig, Martin Bornhäuser, Christian Thiede, Jan Moritz Middeke
Published 2021-04-01