Ntrk1 Promotes Resistance to PD-1 Checkpoint Blockade in Mesenchymal Kras/p53 Mutant Lung Cancer

by Jessica M. Konen, B. Leticia Rodriguez, Jared J. Fradette, Laura Gibson, Denali Davis, Rosalba Minelli, Michael D. Peoples, Jeffrey Kovacs, Alessandro Carugo, Christopher Bristow, Timothy Heffernan, Don L. Gibbons
Published 2019-04-01

ZEB1/NuRD complex suppresses TBC1D2b to stimulate E-cadherin internalization and promote metastasis in lung cancer

by Roxsan Manshouri, Etienne Coyaud, Samrat T. Kundu, David H. Peng, Sabrina A. Stratton, Kendra Alton, Rakhee Bajaj, Jared J. Fradette, Rosalba Minelli, Michael D. Peoples, Alessandro Carugo, Fengju Chen, Christopher Bristow, Jeffrey J. Kovacs, Michelle C. Barton, Tim Heffernan, Chad J. Creighton, Brian Raught, Don L. Gibbons
Published 2019-11-01

High-resolution clonal mapping of multi-organ metastasis in triple negative breast cancer

by Gloria V. Echeverria, Emily Powell, Sahil Seth, Zhongqi Ge, Alessandro Carugo, Christopher Bristow, Michael Peoples, Frederick Robinson, Huan Qiu, Jiansu Shao, Sabrina L. Jeter-Jones, Xiaomei Zhang, Vandhana Ramamoorthy, Shirong Cai, Wenhui Wu, Giulio Draetta, Stacy L. Moulder, William F. Symmans, Jeffrey T. Chang, Timothy P. Heffernan, Helen Piwnica-Worms
Published 2018-11-01

Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers

by Sherille D. Bradley, Amjad H. Talukder, Ivy Lai, Rebecca Davis, Hector Alvarez, Herve Tiriac, Minying Zhang, Yulun Chiu, Brenda Melendez, Kyle R. Jackson, Arjun Katailiha, Heather M. Sonnemann, Fenge Li, Yaan Kang, Na Qiao, Bih-Fang Pan, Philip L. Lorenzi, Mark Hurd, Elizabeth A. Mittendorf, Christine B. Peterson, Milind Javle, Christopher Bristow, Michael Kim, David A. Tuveson, David Hawke, Scott Kopetz, Robert A. Wolff, Patrick Hwu, Anirban Maitra, Jason Roszik, Cassian Yee, Gregory Lizée
Published 2020-10-01