mTOR inhibitors in cancer therapy [version 1; referees: 3 approved]

by Jianling Xie, Xuemin Wang, Christopher G. Proud
Published 2016-08-01

Eukaryotic Elongation Factor 2 Kinase (eEF2K) in Cancer

by Xuemin Wang, Jianling Xie, Christopher G. Proud
Published 2017-11-01

Thioflavin T Monitoring of Guanine Quadruplex Formation in the rs689-Dependent INS Intron 1

by Ana Lages, Christopher G. Proud, John W. Holloway, Igor Vorechovsky
Published 2019-06-01

A high-throughput screening assay for eukaryotic elongation factor 2 kinase inhibitors

by Ting Xiao, Rui Liu, Christopher G. Proud, Ming-Wei Wang
Published 2016-10-01

Identification of DNA response elements regulating expression of CCAAT/enhancer-binding protein (C/EBP) β and δ and MAP kinase-interacting kinases during early adipogenesis

by James E. Merrett, Tao Bo, Peter J. Psaltis, Christopher G. Proud
Published 2020-01-01

Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling.

by Aruna D Balgi, Bruno D Fonseca, Elizabeth Donohue, Trevor C F Tsang, Patrick Lajoie, Christopher G Proud, Ivan R Nabi, Michel Roberge
Published 2009-09-01

Deletion of Rptor in Preosteoblasts Reveals a Role for the Mammalian Target of Rapamycin Complex 1 (mTORC1) Complex in Dietary‐Induced Changes to Bone Mass and Glucose Homeostasis...

by Pawanrat Tangseefa, Sally K. Martin, Agnieszka Arthur, Vasilios Panagopoulos, Amanda J. Page, Gary A. Wittert, Christopher G. Proud, Stephen Fitter, Andrew C.W. Zannettino
Published 2021-05-01

Two-Stage Translational Control of Dentate Gyrus LTP Consolidation Is Mediated by Sustained BDNF-TrkB Signaling to MNK

by Debabrata Panja, Justin W. Kenney, Laura D’Andrea, Francesca Zalfa, Anni Vedeler, Karin Wibrand, Rikiro Fukunaga, Claudia Bagni, Christopher G. Proud, Clive R. Bramham
Published 2014-11-01

The eEF2 kinase-induced STAT3 inactivation inhibits lung cancer cell proliferation by phosphorylation of PKM2

by Min Xiao, Jianling Xie, Yu Wu, Genzhu Wang, Xin Qi, Zailiang Liu, Yuying Wang, Xuemin Wang, Ashfaqul Hoque, Jon Oakhill, Christopher G. Proud, Jing Li
Published 2020-02-01

Disabling MNK protein kinases promotes oxidative metabolism and protects against diet-induced obesity

by Lauren Y. Sandeman, Wan Xian Kang, Xuemin Wang, Kirk B. Jensen, Derick Wong, Tao Bo, Ling Gao, Jiajun Zhao, Christopher D. Byrne, Amanda J. Page, Christopher G. Proud
Published 2020-12-01

The mTORC1 complex in pre-osteoblasts regulates whole-body energy metabolism independently of osteocalcin

by Pawanrat Tangseefa, Sally K. Martin, Peck Yin Chin, James Breen, Chui Yan Mah, Paul A. Baldock, Gary A. Wittert, Amanda J. Page, Christopher G. Proud, Stephen Fitter, Andrew C. W. Zannettino
Published 2021-02-01

Regulation of protein synthesis in lymphoblasts from vanishing white matter patients

by Barbara van Kollenburg, Adri A.M. Thomas, Gerre Vermeulen, Gesina A.M. Bertrand, Carola G.M. van Berkel, Jan C. Pronk, Christopher G. Proud, Marjo S. van der Knaap, Gert C. Scheper
Published 2006-03-01

Vanishing white matter: Eukaryotic initiation factor 2B model and the impact of missense mutations

by Inna Slynko, Stephanie Nguyen, Eline M. C. Hamilton, Lisanne E. Wisse, Iwan J. P. deEsch, Chris deGraaf, John B. Bruning, Christopher G. Proud, Truus E. M. Abbink, Marjo S. van derKnaap
Published 2021-03-01

Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology.

by Patience T Brace, Liku B Tezera, Magdalena K Bielecka, Toby Mellows, Diana Garay, Shuye Tian, Lucinda Rand, Justin Green, Sanjay Jogai, Andrew J Steele, Timothy M Millar, Tilman Sanchez-Elsner, Jon S Friedland, Christopher G Proud, Paul T Elkington
Published 2017-06-01

Proteomic and Metabolomic Analyses of Vanishing White Matter Mouse Astrocytes Reveal Deregulation of ER Functions

by Lisanne E. Wisse, Renske Penning, Esther A. Zaal, Carola G. M. van Berkel, Timo J. ter Braak, Emiel Polder, Justin W. Kenney, Christopher G. Proud, Celia R. Berkers, Maarten A. F. Altelaar, Dave Speijer, Marjo S. van der Knaap, Truus E. M. Abbink
Published 2017-12-01

The composition of the gut microbiota following early-life antibiotic exposure affects host health and longevity in later life

by Miriam A. Lynn, Georgina Eden, Feargal J. Ryan, Julien Bensalem, Xuemin Wang, Stephen J. Blake, Jocelyn M. Choo, Yee Tee Chern, Anastasia Sribnaia, Jane James, Saoirse C. Benson, Lauren Sandeman, Jianling Xie, Sofia Hassiotis, Emily W. Sun, Alyce M. Martin, Marianne D. Keller, Damien J. Keating, Timothy J. Sargeant, Christopher G. Proud, Steve L. Wesselingh, Geraint B. Rogers, David J. Lynn
Published 2021-08-01