The Dynamic Roles of TGF-β Signalling in EBV-Associated Cancers

by Sharmila Velapasamy, Christopher W. Dawson, Lawrence S. Young, Ian C. Paterson, Lee Fah Yap
Published 2018-07-01

The Major Constituent of Green Tea, Epigallocatechin-3-Gallate (EGCG), Inhibits the Growth of HPV18-Infected Keratinocytes by Stimulating Proteasomal Turnover of the E6 and E7 Onco...

by Jason K.W. Yap, Sean T. Kehoe, Ciaran B.J. Woodman, Christopher W. Dawson
Published 2021-04-01

The EBV-Encoded Oncoprotein, LMP1, Recruits and Transforms Fibroblasts via an ERK-MAPK-Dependent Mechanism

by Alexandra M Davis, Abigail Rapley, Christopher W Dawson, Lawrence S Young, Mhairi A Morris
Published 2021-08-01

The Role of EBV-Encoded LMP1 in the NPC Tumor Microenvironment: From Function to Therapy

by Angela Kwok-Fung Lo, Christopher W. Dawson, Hong Lok Lung, Ka-Leung Wong, Lawrence S. Young
Published 2021-02-01

The Therapeutic Potential of Targeting BARF1 in EBV-Associated Malignancies

by Angela Kwok-Fung Lo, Christopher W. Dawson, Hong Lok Lung, Ka-Leung Wong, Lawrence S. Young
Published 2020-07-01

Aberrant activation of the Hedgehog signalling pathway in squamous cell carcinoma of the vulva as a potential target for cancer therapy

by Jason K. W. Yap, Khalil Uddin, Rachel Pounds, Danielle O’Neill, Sean Kehoe, Raji Ganesan, Christopher W. Dawson
Published 2021-09-01

The Epstein-Barr Virus-Encoded EBNA1 Protein Activates the Bone Morphogenic Protein (BMP) Signalling Pathway to Promote Carcinoma Cell Migration

by Hannah E. Bridgewater, Kathryn L. Date, John D. O’Neil, Chunfang Hu, John R. Arrand, Christopher W. Dawson, Lawrence S. Young
Published 2020-07-01

The EBV-Encoded Oncoprotein, LMP1, Induces an Epithelial-to-Mesenchymal Transition (EMT) via Its CTAR1 Domain through Integrin-Mediated ERK-MAPK Signalling

by Mhairi A. Morris, Louise Laverick, Wenbin Wei, Alexandra M. Davis, Samantha O’Neill, Liam Wood, Jack Wright, Christopher W. Dawson, Lawrence S. Young
Published 2018-05-01

A global view of the oncogenic landscape in nasopharyngeal carcinoma: an integrated analysis at the genetic and expression levels.

by Chunfang Hu, Wenbin Wei, Xiaoyi Chen, Ciaran B Woodman, Yunhong Yao, John M Nicholls, Irène Joab, Sim K Sihota, Jian-Yong Shao, K Dalia Derkaoui, Aicha Amari, Stephanie L Maloney, Andrew I Bell, Paul G Murray, Christopher W Dawson, Lawrence S Young, John R Arrand
Published 2012-01-01

Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape

by Jeff P. Bruce, Ka-Fai To, Vivian W. Y. Lui, Grace T. Y. Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y. Yip, Brigette B. Y. Ma, John K. S. Woo, Edwin P. Hui, Michael K. F. Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y. Y. Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie Prokopec, Man Wu, Johnny S. H. Kwan, Yuchen Liu, Jason Y. K. Chan, C. Andrew van Hasselt, Lawrence S. Young, Christopher W. Dawson, Ian C. Paterson, Lee-Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T. C. Chan, Trevor J. Pugh, Kwok-Wai Lo
Published 2021-07-01