SIRT1, Is It a Tumor Promoter or Tumor Suppressor?

by Chu-Xia Deng
Published 2009-01-01

PARP-1 inhibitors: are they the long-sought genetically specific drugs for BRCA1/2-associated breast cancers?

by Joseph A. De Soto, Chu-Xia Deng
Published 2006-01-01

RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector

by Vivek Shukla, Xavier Coumoul, Chu-Xia Deng
Published 2007-01-01

SRC-3, a Steroid Receptor Coactivator: Implication in Cancer

by Licen Li, Chu-Xia Deng, Qiang Chen
Published 2021-04-01

Liver Steatosis and Increased ChREBP Expression in Mice Carrying a Liver Specific SIRT1 Null Mutation under a Normal Feeding Condition

by Rui-Hong Wang, Cuiling Li, Chu-Xia Deng
Published 2010-01-01

Aberrant p63 and WT-1 expression in myoepithelial cells of pregnancy-associated breast cancer: implications for tumor aggressiveness and invasiveness

by Zheli Xu, Wan Wang, Chu-Xia Deng, Yan-gao Man
Published 2009-01-01

Murine Wee1 Plays a Critical Role in Cell Cycle Regulation and Pre-Implantation Stages of Embryonic Development

by Yohei Tominaga, Cuiling Li, Rui-Hong Wang, Chu-Xia Deng
Published 2006-01-01

Anterior Visceral Endoderm SMAD4 Signaling Specifies Anterior Embryonic Patterning and Head Induction in Mice

by Cuiling Li, Yi-Ping Li, Xin-Yuan Fu, Chu-Xia Deng
Published 2010-01-01

Sexual Fate Change of XX Germ Cells Caused by the Deletion of SMAD4 and STRA8 Independent of Somatic Sex Reprogramming.

by Quan Wu, Kurumi Fukuda, Yuzuru Kato, Zhi Zhou, Chu-Xia Deng, Yumiko Saga
Published 2016-09-01

Correlated alterations in prostate basal cell layer and basement membrane

by Aijun Liu, Lixin Wei, William A. Gardner, Chu-Xia Deng, Yan-Gao Man
Published 2009-01-01

Identification and characterization of cancer initiating cells from BRCA1 related mammary tumors using markers for normal mammary stem cells

by Athanassios Vassilopoulos, Rui-Hong Wang, Constantinos Petrovas, David Ambrozak, Richard Koup, Chu-Xia Deng
Published 2008-01-01

SRp20 is a proto-oncogene critical for cell proliferation and tumor induction and maintenance

by Rong Jia, Cuiling Li, J. Philip McCoy, Chu-Xia Deng, Zhi-Ming Zheng
Published 2010-01-01

Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6[S]

by Rongya Tao, Xiwen Xiong, Ronald A. DePinho, Chu-Xia Deng, X. Charlie Dong
Published 2013-10-01

A PP1-binding motif present in BRCA1 plays a role in its DNA repair function

by Young-Mi Yu, Serena M. Pace, Susan R. Allen, Chu-Xia Deng, Lih-Ching Hsu
Published 2008-01-01

SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mitotic Clonal Expansion

by Qiang Chen, Wenhui Hao, Cuiying Xiao, Ruihong Wang, Xiaoling Xu, Huiyan Lu, Weiping Chen, Chu-Xia Deng
Published 2017-03-01

Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.

by Eri Maria Sol, Sebastian A Wagner, Brian T Weinert, Amit Kumar, Hyun-Seok Kim, Chu-Xia Deng, Chunaram Choudhary
Published 2012-01-01

Oxygen‐Enriched Metal‐Phenolic X‐Ray Nanoprocessor for Cancer Radio‐Radiodynamic Therapy in Combination with Checkpoint Blockade Immunotherapy

by Wei Sang, Lisi Xie, Guohao Wang, Jie Li, Zhan Zhang, Bei Li, Sen Guo, Chu‐Xia Deng, Yunlu Dai
Published 2021-02-01

Depletion of ceramides with very long chain fatty acids causes defective skin permeability barrier function, and neonatal lethality in ELOVL4 deficient mice

by Wenmei Li, Roger Sandhoff, Mari Kono, Patricia Zerfas, Vickie Hoffmann, Bryan Char-Hoa Ding, Richard L. Proia, Chu-Xia Deng
Published 2007-01-01

SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids.

by Takamasa Tobita, Jorge Guzman-Lepe, Kazuki Takeishi, Toshimasa Nakao, Yang Wang, Fanying Meng, Chu-Xia Deng, Alexandra Collin de l'Hortet, Alejandro Soto-Gutierrez
Published 2016-01-01

The metabolic footprint during adipocyte commitment highlights ceramide modulation as an adequate approach for obesity treatment

by Weilong Hou, Qiang Chen, Haitao Wang, Pengxiang Qiu, Xueying Lyu, Weiping Chen, Melvin L.K. Chua, Y. Eugene Chinn, Chu-Xia Deng, Ruihong Wang
Published 2020-01-01