Chuan He
Chuan He () is a
Chinese-American chemical biologist. He currently serves as the John T. Wilson Distinguished Service Professor at the
University of Chicago, and an Investigator of the
Howard Hughes Medical Institute. He is best known for his work in discovering and deciphering reversible
RNA methylation in post-transcriptional gene expression regulation. He was awarded the 2023
Wolf Prize in Chemistry for his work in discovering and deciphering reversible
RNA methylation in post-transcriptional gene expression regulation in addition to his contributions to the invention of TAB-seq, a biochemical method that can map 5-hydroxymethylcytosine (5hmC) at base-resolution genome-wide, as well as hmC-Seal, a method that covalently labels 5hmC for its detection and profiling.
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