Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide–PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential t...

by Peng Lyu, Lilin Ge, Rui Ma, Ran Wei, Cian M. McCrudden, Tianbao Chen, Chris Shaw, Hang Fai Kwok
Published 2018-09-01

TAZ expression as a prognostic indicator in colorectal cancer.

by Hiu-Fung Yuen, Cian M McCrudden, Yu-Han Huang, Jill M Tham, Xiaoqian Zhang, Qi Zeng, Shu-Dong Zhang, WanJin Hong
Published 2013-01-01

The prognostic significance of Cdc6 and Cdt1 in breast cancer

by Ravikiran Mahadevappa, Henrique Neves, Shun Ming Yuen, Yuchen Bai, Cian M. McCrudden, Hiu Fung Yuen, Qing Wen, Shu Dong Zhang, Hang Fai Kwok
Published 2017-04-01

Systemic RALA/iNOS Nanoparticles: A Potent Gene Therapy for Metastatic Breast Cancer Coupled as a Biomarker of Treatment

by Cian M. McCrudden, John W. McBride, Joanne McCaffrey, Ahlam A. Ali, Nicholas J. Dunne, Vicky L. Kett, Jonathan A. Coulter, Tracy Robson, Helen O. McCarthy
Published 2017-03-01

Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Corneal Epithelium Using a Modified Cell-Penetrating Peptide

by Davide Schiroli, María J. Gómara, Eleonora Maurizi, Sarah D. Atkinson, Laura Mairs, Kathleen A. Christie, Diego F. Cobice, Cian M. McCrudden, M. Andrew Nesbit, Isabel Haro, Tara Moore
Published 2019-09-01

Gene therapy with RALA/iNOS composite nanoparticles significantly enhances survival in a model of metastatic prostate cancer

by Cian M. McCrudden, John W. McBride, Joanne McCaffrey, Emma M. McErlean, Nicholas J. Dunne, Vicky L. Kett, Jonathan A. Coulter, Tracy Robson, Helen O. McCarthy
Published 2018-06-01

Vasoactivity of rucaparib, a PARP-1 inhibitor, is a complex process that involves myosin light chain kinase, P2 receptors, and PARP itself.

by Cian M McCrudden, Martin G O'Rourke, Kim E Cherry, Hiu-Fung Yuen, Declan O'Rourke, Muhammad Babur, Brian A Telfer, Huw D Thomas, Patrick Keane, Thiagarajan Nambirajan, Chris Hagan, Joe M O'Sullivan, Chris Shaw, Kaye J Williams, Nicola J Curtin, David G Hirst, Tracy Robson
Published 2015-01-01