NCS 613, a Potent PDE4 Inhibitor, Displays Anti-Inflammatory and Anti-Proliferative Properties on A549 Lung Epithelial Cells and Human Lung Adenocarcinoma Explants

by Issaka Yougbare, Issaka Yougbare, Lazare Belemnaba, Caroline Morin, Abdurazzag Abusnina, Yannick F. Senouvo, Thérèse Keravis, Claire Lugnier, Claire Lugnier, Eric Rousseau, Eric Rousseau
Published 2020-08-01

The Endocrine Function of the Heart: Physiology and Involvements of Natriuretic Peptides and Cyclic Nucleotide Phosphodiesterases in Heart Failure

by Claire Lugnier, Alain Meyer, Anne Charloux, Emmanuel Andrès, Bernard Gény, Samy Talha
Published 2019-10-01

Disease progression in MRL/lpr lupus-prone mice is reduced by NCS 613, a specific cyclic nucleotide phosphodiesterase type 4 (PDE4) inhibitor.

by Thérèse Keravis, Fanny Monneaux, Issaka Yougbaré, Lucien Gazi, Jean-Jacques Bourguignon, Sylviane Muller, Claire Lugnier
Published 2012-01-01

Concerted regulation of cGMP and cAMP phosphodiesterases in early cardiac hypertrophy induced by angiotensin II.

by Walid Mokni, Thérèse Keravis, Nelly Etienne-Selloum, Alison Walter, Modou O Kane, Valérie B Schini-Kerth, Claire Lugnier
Published 2010-01-01

Effect of the Phosphodiesterase 5 Inhibitor Sildenafil on Ischemia-Reperfusion-Induced Muscle Mitochondrial Dysfunction and Oxidative Stress

by Liliane Tetsi, Anne-Laure Charles, Isabelle Georg, Fabienne Goupilleau, Anne Lejay, Samy Talha, Myriam Maumy-Bertrand, Claire Lugnier, Bernard Geny
Published 2019-04-01

Delphinidin Inhibits Tumor Growth by Acting on VEGF Signalling in Endothelial Cells.

by Thérèse Keravis, Laure Favot, Abdurrazag A Abusnina, Anita Anton, Hélène Justiniano, Raffaella Soleti, Eid Alabed Alibrahim, Gilles Simard, Ramaroson Andriantsitohaina, Claire Lugnier
Published 2015-01-01