Vaccines against Human Carcinomas: Strategies to Improve Antitumor Immune Responses

by Claudia Palena, Jeffrey Schlom
Published 2010-01-01

Loss of the Cyclin-Dependent Kinase Inhibitor 1 in the Context of Brachyury-Mediated Phenotypic Plasticity Drives Tumor Resistance to Immune Attack

by Duane H. Hamilton, Kristen K. McCampbell, Claudia Palena
Published 2018-05-01

445 Blockade of the inhibitory collagen receptor LAIR-1 with NC410, a LAIR2-Fc fusion protein, enhances anti-tumor activity of the bifunctional fusion protein bintrafusp alfa

by Jeffrey Schlom, Claudia Palena, Lucas Horn, Linjie Tian, Dallas Flies, Linda Liu, Solomon Langermann
Published 2020-11-01

A novel bifunctional anti-PD-L1/TGF-β Trap fusion protein (M7824) efficiently reverts mesenchymalization of human lung cancer cells

by Justin M. David, Charli Dominguez, Kristen K. McCampbell, James L. Gulley, Jeffrey Schlom, Claudia Palena
Published 2017-10-01

Vaccine Increases the Diversity and Activation of Intratumoral T Cells in the Context of Combination Immunotherapy

by Lucas A. Horn, Kristen Fousek, Duane H. Hamilton, James W. Hodge, John A. Zebala, Dean Y. Maeda, Jeffrey Schlom, Claudia Palena
Published 2021-02-01

The Use of a Humanized NSG-β2m−/− Model for Investigation of Immune and Anti-tumor Effects Mediated by the Bifunctional Immunotherapeutic Bintrafusp Alfa

by Y. Maurice Morillon, Claire Smalley Rumfield, Samuel T. Pellom, Ariana Sabzevari, Nicholas T. Roller, Lucas A. Horn, Caroline Jochems, Claudia Palena, John W. Greiner, Jeffrey Schlom
Published 2020-04-01

Brachyury-YAP Regulatory Axis Drives Stemness and Growth in Cancer

by Sagar R. Shah, Justin M. David, Nathaniel D. Tippens, Ahmed Mohyeldin, Juan C. Martinez-Gutierrez, Sara Ganaha, Paula Schiapparelli, Duane H. Hamilton, Claudia Palena, Andre Levchenko, Alfredo Quiñones-Hinojosa
Published 2017-10-01

Identification of Immune Cell Infiltration in Murine Pheochromocytoma during Combined Mannan-BAM, TLR Ligand, and Anti-CD40 Antibody-Based Immunotherapy

by Ondrej Uher, Thanh-Truc Huynh, Boqun Zhu, Lucas A. Horn, Veronika Caisova, Katerina Hadrava Vanova, Rogelio Medina, Herui Wang, Claudia Palena, Jindrich Chmelar, Zhengping Zhuang, Jan Zenka, Karel Pacak
Published 2021-08-01

Phase I trial of HuMax-IL8 (BMS-986253), an anti-IL-8 monoclonal antibody, in patients with metastatic or unresectable solid tumors

by Marijo Bilusic, Christopher R. Heery, Julie M. Collins, Renee N. Donahue, Claudia Palena, Ravi A. Madan, Fatima Karzai, Jennifer L. Marté, Julius Strauss, Margaret E. Gatti-Mays, Jeffrey Schlom, James L. Gulley
Published 2019-09-01

Improving the Odds in Advanced Breast Cancer With Combination Immunotherapy: Stepwise Addition of Vaccine, Immune Checkpoint Inhibitor, Chemotherapy, and HDAC Inhibitor in Advanced...

by Margaret E. Gatti-Mays, Sofia R. Gameiro, Yohei Ozawa, Karin M. Knudson, Kristin C. Hicks, Claudia Palena, Lisa M. Cordes, Seth M. Steinberg, Deneise Francis, Fatima Karzai, Stanley Lipkowitz, Renee N. Donahue, Caroline Jochems, Jeffrey Schlom, James L. Gulley
Published 2021-03-01

Phase I study of a multitargeted recombinant Ad5 PSA/MUC-1/brachyury-based immunotherapy vaccine in patients with metastatic castration-resistant prostate cancer (mCRPC)

by Renee N Donahue, Jeffrey Schlom, James L Gulley, Ravi A Madan, Claudia Palena, Caroline Jochems, Shahrooz Rabizadeh, Patrick Soon-Shiong, Sheri McMahon, Julius Strauss, Marijo Bilusic, Fatima Karzai, Houssein Abdul Sater, Jennifer L Marté, Yo-Ting Tsai, Jason Redman, Charalampos Floudas
Published 2021-03-01