Improper tagging of the non-essential small capsid protein VP26 impairs nuclear capsid egress of herpes simplex virus.

by Claus-Henning Nagel, Katinka Döhner, Anne Binz, Rudolf Bauerfeind, Beate Sodeik
Published 2012-01-01

Interaction between the cellular E3 ubiquitin ligase SIAH-1 and the viral immediate-early protein ICP0 enables efficient replication of Herpes Simplex Virus type 2 in vivo.

by Julia S Czechowicz, Claus-Henning Nagel, Maike Voges, Michael Spohn, Martha M Eibl, Joachim Hauber
Published 2018-01-01

A herpes simplex virus-derived replicative vector expressing LIF limits experimental demyelinating disease and modulates autoimmunity.

by Michaela Nygårdas, Henrik Paavilainen, Nadine Müther, Claus-Henning Nagel, Matias Röyttä, Beate Sodeik, Veijo Hukkanen
Published 2013-01-01

The Herpes Simplex Virus Protein pUL31 Escorts Nucleocapsids to Sites of Nuclear Egress, a Process Coordinated by Its N-Terminal Domain.

by Christina Funk, Melanie Ott, Verena Raschbichler, Claus-Henning Nagel, Anne Binz, Beate Sodeik, Rudolf Bauerfeind, Susanne M Bailer
Published 2015-06-01

Inner tegument proteins of Herpes Simplex Virus are sufficient for intracellular capsid motility in neurons but not for axonal targeting.

by Anna Buch, Oliver Müller, Lyudmila Ivanova, Katinka Döhner, Dagmara Bialy, Jens B Bosse, Anja Pohlmann, Anne Binz, Maike Hegemann, Claus-Henning Nagel, Martin Koltzenburg, Abel Viejo-Borbolla, Bodo Rosenhahn, Rudolf Bauerfeind, Beate Sodeik
Published 2017-12-01