Proteolytic Regulation of Parathyroid Hormone-Related Protein: Functional Implications for Skeletal Malignancy

by Jeremy S. Frieling, Conor C. Lynch
Published 2019-06-01

Cutting to the Chase: How Matrix Metalloproteinase-2 Activity Controls Breast-Cancer-to-Bone Metastasis

by Marilena Tauro, Conor C. Lynch
Published 2018-06-01

Prostate cancer-derived MMP-3 controls intrinsic cell growth and extrinsic angiogenesis

by Jeremy S. Frieling, Tao Li, Marilena Tauro, Conor C. Lynch
Published 2020-10-01

Multifaceted Roles for Macrophages in Prostate Cancer Skeletal Metastasis

by Chen Hao Lo, Chen Hao Lo, Conor C. Lynch
Published 2018-05-01

Computational modeling reveals a key role for polarized myeloid cells in controlling osteoclast activity during bone injury repair

by Chen Hao Lo, Etienne Baratchart, David Basanta, Conor C. Lynch
Published 2021-03-01

Cleavage of E-Cadherin by Matrix Metalloproteinase-7 Promotes Cellular Proliferation in Nontransformed Cell Lines via Activation of RhoA

by Conor C. Lynch, Tracy Vargo-Gogola, Lynn M. Matrisian, Barbara Fingleton
Published 2010-01-01

Fractionated Follow-Up Chemotherapy Delays the Onset of Resistance in Bone Metastatic Prostate Cancer

by Pranav I. Warman, Artem Kaznatcheev, Arturo Araujo, Conor C. Lynch, David Basanta
Published 2018-04-01

An osteoblast-derived proteinase controls tumor cell survival via TGF-beta activation in the bone microenvironment.

by Sophie Thiolloy, James R Edwards, Barbara Fingleton, Daniel B Rifkin, Lynn M Matrisian, Conor C Lynch
Published 2012-01-01

Modeling Osteocyte Network Formation: Healthy and Cancerous Environments

by Jake P. Taylor-King, Jake P. Taylor-King, Jake P. Taylor-King, Pascal R. Buenzli, S. Jon Chapman, Conor C. Lynch, David Basanta
Published 2020-07-01

An MMP13-selective inhibitor delays primary tumor growth and the onset of tumor-associated osteolytic lesions in experimental models of breast cancer.

by Manisha Shah, Dexing Huang, Tony Blick, Andrea Connor, Lawrence A Reiter, Joel R Hardink, Conor C Lynch, Mark Waltham, Erik W Thompson
Published 2012-01-01

Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer

by Jeremy J. McGuire, Jeremy S. Frieling, Chen Hao Lo, Tao Li, Ayaz Muhammad, Harshani R. Lawrence, Nicholas J. Lawrence, Leah M. Cook, Conor C. Lynch
Published 2021-02-01

Quantification and Optimization of Standard-of-Care Therapy to Delay the Emergence of Resistant Bone Metastatic Prostate Cancer

by Arturo Araujo, Leah M. Cook, Jeremy S. Frieling, Winston Tan, John A. Copland, Manish Kohli, Shilpa Gupta, Jasreman Dhillon, Julio Pow-Sang, Conor C. Lynch, David Basanta
Published 2021-02-01

EphA2 Is a Clinically Relevant Target for Breast Cancer Bone Metastatic Disease

by David B Vaught, Alyssa R Merkel, Conor C Lynch, James Edwards, Mohammed Noor Tantawy, Timothy Hilliard, Shan Wang, Todd Peterson, Rachelle W Johnson, Julie A Sterling, Dana Brantley‐Sieders
Published 2021-04-01

Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity

by Brian C. Betts, Brian C. Betts, Brian C. Betts, Frederick L. Locke, Frederick L. Locke, Elizabeth M. Sagatys, Joseph Pidala, Joseph Pidala, Kelly Walton, Kelly Walton, Meghan Menges, Jordan Reff, Asim Saha, Asim Saha, Julie Y. Djeu, John V. Kiluk, Marie C. Lee, Jongphil Kim, Chang Won Kang, Chih-Hang Anthony Tang, Jeremy Frieling, Conor C. Lynch, Alan List, Paulo C. Rodriguez, Bruce R. Blazar, Bruce R. Blazar, Jose R. Conejo-Garcia, Juan R. Del Valle, Chih-Chi Andrew Hu, Claudio Anasetti, Claudio Anasetti
Published 2018-12-01