Evidence That Tumor Microenvironment Initiates Epithelial-To-Mesenchymal Transition and Calebin A can Suppress it in Colorectal Cancer Cells

by Constanze Buhrmann, Constanze Buhrmann, Aranka Brockmueller, Choudhary Harsha, Ajaikumar B. Kunnumakkara, Peter Kubatka, Bharat B. Aggarwal, Mehdi Shakibaei
Published 2021-07-01

Multitargeting Effects of Calebin A on Malignancy of CRC Cells in Multicellular Tumor Microenvironment

by Constanze Buhrmann, Constanze Buhrmann, Ajaikumar B. Kunnumakkara, Aviral Kumar, Marek Samec, Peter Kubatka, Bharat B. Aggarwal, Mehdi Shakibaei
Published 2021-09-01

Resveratrol Suppresses Cross-Talk between Colorectal Cancer Cells and Stromal Cells in Multicellular Tumor Microenvironment: A Bridge between In Vitro and In Vivo Tumor Microenviro...

by Constanze Buhrmann, Parviz Shayan, Aranka Brockmueller, Mehdi Shakibaei
Published 2020-09-01

Resveratrol Regulates Colorectal Cancer Cell Invasion by Modulation of Focal Adhesion Molecules

by Constanze Buhrmann, Parviz Shayan, Ajay Goel, Mehdi Shakibaei
Published 2017-09-01

Resveratrol downregulates inflammatory pathway activated by lymphotoxin α (TNF-β) in articular chondrocytes: Comparison with TNF-α.

by Constanze Buhrmann, Bastian Popper, Bharat B Aggarwal, Mehdi Shakibaei
Published 2017-01-01

Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells

by Constanze Buhrmann, Parviz Shayan, Bastian Popper, Ajay Goel, Mehdi Shakibaei
Published 2016-03-01

Curcumin Attenuates Environment-Derived Osteoarthritis by Sox9/NF-kB Signaling Axis

by Constanze Buhrmann, Aranka Brockmueller, Anna-Lena Mueller, Parviz Shayan, Mehdi Shakibaei
Published 2021-07-01

Herbal Remedies as Potential in Cartilage Tissue Engineering: An Overview of New Therapeutic Approaches and Strategies

by Constanze Buhrmann, Ali Honarvar, Mohsen Setayeshmehr, Saeed Karbasi, Mehdi Shakibaei, Ali Valiani
Published 2020-07-01

Curcumin suppresses crosstalk between colon cancer stem cells and stromal fibroblasts in the tumor microenvironment: potential role of EMT.

by Constanze Buhrmann, Patricia Kraehe, Cora Lueders, Parviz Shayan, Ajay Goel, Mehdi Shakibaei
Published 2014-01-01

Curcumin chemosensitizes 5-fluorouracil resistant MMR-deficient human colon cancer cells in high density cultures.

by Mehdi Shakibaei, Constanze Buhrmann, Patricia Kraehe, Parviz Shayan, Cora Lueders, Ajay Goel
Published 2014-01-01

Calebin A Potentiates the Effect of 5-FU and TNF-β (Lymphotoxin α) against Human Colorectal Cancer Cells: Potential Role of NF-κB

by Constanze Buhrmann, Ajaikumar B. Kunnumakkara, Bastian Popper, Muhammed Majeed, Bharat B. Aggarwal, Mehdi Shakibaei
Published 2020-03-01

Organophosphorus Compounds and MAPK Signaling Pathways

by Tahereh Farkhondeh, Omid Mehrpour, Constanze Buhrmann, Ali Mohammad Pourbagher-Shahri, Mehdi Shakibaei, Saeed Samarghandian
Published 2020-06-01

Resveratrol mediated modulation of Sirt-1/Runx2 promotes osteogenic differentiation of mesenchymal stem cells: potential role of Runx2 deacetylation.

by Mehdi Shakibaei, Parviz Shayan, Franziska Busch, Constance Aldinger, Constanze Buhrmann, Cora Lueders, Ali Mobasheri
Published 2012-01-01

Induction of the Epithelial-to-Mesenchymal Transition of Human Colorectal Cancer by Human TNF-β (Lymphotoxin) and its Reversal by Resveratrol

by Constanze Buhrmann, Mina Yazdi, Bastian Popper, Ajaikumar B. Kunnumakkara, Bharat B. Aggarwal, Mehdi Shakibaei
Published 2019-03-01

Targeting NF-kB Signaling by Calebin A, a Compound of Turmeric, in Multicellular Tumor Microenvironment: Potential Role of Apoptosis Induction in CRC Cells

by Constanze Buhrmann, Parviz Shayan, Kishore Banik, Ajaikumar B. Kunnumakkara, Peter Kubatka, Lenka Koklesova, Mehdi Shakibaei
Published 2020-07-01

IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: involvement of Src/PI-3K/AKT pathway.

by Azadeh Montaseri, Franziska Busch, Ali Mobasheri, Constanze Buhrmann, Constance Aldinger, Jafar Soleimani Rad, Mehdi Shakibaei
Published 2011-01-01

Resveratrol Chemosensitizes TNF-β-Induced Survival of 5-FU-Treated Colorectal Cancer Cells

by Constanze Buhrmann, Mina Yazdi, Bastian Popper, Parviz Shayan, Ajay Goel, Bharat B. Aggarwal, Mehdi Shakibaei
Published 2018-07-01

Neuronal aldosterone elicits a distinct genomic response in pain signaling molecules contributing to inflammatory pain

by Mohammed Shaqura, Li Li, Doaa M. Mohamed, Xiongjuan Li, Sascha Treskatsch, Constanze Buhrmann, Mehdi Shakibaei, Antje Beyer, Shaaban A. Mousa, Michael Schäfer
Published 2020-06-01

Carotenoids in Cancer Apoptosis—The Road <i>from Bench to Bedside</i> and Back

by Lenka Koklesova, Alena Liskova, Marek Samec, Constanze Buhrmann, Samson Mathews Samuel, Elizabeth Varghese, Milad Ashrafizadeh, Masoud Najafi, Mehdi Shakibaei, Dietrich Büsselberg, Frank A. Giordano, Olga Golubnitschaja, Peter Kubatka
Published 2020-08-01