Uncoupling of glycolysis from glucose oxidation accompanies the development of heart failure with preserved ejection fraction

by Natasha Fillmore, Jody L. Levasseur, Arata Fukushima, Cory S. Wagg, Wei Wang, Jason R. B. Dyck, Gary D. Lopaschuk
Published 2018-03-01

Insulin directly stimulates mitochondrial glucose oxidation in the heart

by Qutuba G. Karwi, Cory S. Wagg, Tariq R. Altamimi, Golam M. Uddin, Kim L. Ho, Ahmed M. Darwesh, John M. Seubert, Gary D. Lopaschuk
Published 2020-12-01

Targeting the glucagon receptor improves cardiac function and enhances insulin sensitivity following a myocardial infarction

by Qutuba G. Karwi, Liyan Zhang, Cory S. Wagg, Wang Wang, Manoj Ghandi, Dung Thai, Hai Yan, John R. Ussher, Gavin Y. Oudit, Gary D. Lopaschuk
Published 2019-01-01

Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure

by Golam M. Uddin, Liyan Zhang, Saumya Shah, Arata Fukushima, Cory S. Wagg, Keshav Gopal, Rami Al Batran, Simran Pherwani, Kim L. Ho, Jamie Boisvenue, Qutuba G. Karwi, Tariq Altamimi, David S. Wishart, Jason R. B. Dyck, John R. Ussher, Gavin Y. Oudit, Gary D. Lopaschuk
Published 2019-07-01