Physical and Functional HAT/HDAC Interplay Regulates Protein Acetylation Balance

by Alessia Peserico, Cristiano Simone
Published 2011-01-01

Special Agents Hunting Down Women Silent Killer: The Emerging Role of the p38α Kinase

by Valentina Grossi, Cristiano Simone
Published 2012-01-01

Playing on the Dark Side: SMYD3 Acts as a Cancer Genome Keeper in Gastrointestinal Malignancies

by Paola Sanese, Candida Fasano, Cristiano Simone
Published 2021-09-01

Updates from the Intestinal Front Line: Autophagic Weapons against Inflammation and Cancer

by Cristiano Simone, Alessia Peserico, Federica Madia, Valentina Grossi
Published 2012-08-01

SMYD3: An Oncogenic Driver Targeting Epigenetic Regulation and Signaling Pathways

by Cinzia Bottino, Alessia Peserico, Cristiano Simone, Giuseppina Caretti
Published 2020-01-01

FOXO3 on the Road to Longevity: Lessons From SNPs and Chromatin Hubs

by Paola Sanese, Giovanna Forte, Vittoria Disciglio, Valentina Grossi, Cristiano Simone
Published 2019-01-01

FOXO3a from the Nucleus to the Mitochondria: A Round Trip in Cellular Stress Response

by Candida Fasano, Vittoria Disciglio, Stefania Bertora, Martina Lepore Signorile, Cristiano Simone
Published 2019-09-01

Chasing the FOXO3: Insights into Its New Mitochondrial Lair in Colorectal Cancer Landscape

by Valentina Grossi, Candida Fasano, Valentina Celestini, Martina Lepore Signorile, Paola Sanese, Cristiano Simone
Published 2019-03-01

From Genetics to Histomolecular Characterization: An Insight into Colorectal Carcinogenesis in Lynch Syndrome

by Martina Lepore Signorile, Vittoria Disciglio, Gabriella Di Carlo, Antonio Pisani, Cristiano Simone, Giuseppe Ingravallo
Published 2021-06-01

Germline pathogenic variant in PIK3CA leading to symmetrical overgrowth with marked macrocephaly and mild global developmental delay

by Marcella Zollino, Carlotta Ranieri, Valentina Grossi, Chiara Leoni, Serena Lattante, Daniela Mazzà, Cristiano Simone, Nicoletta Resta
Published 2019-08-01

<i>APC</i> Splicing Mutations Leading to In-Frame Exon 12 or Exon 13 Skipping Are Rare Events in FAP Pathogenesis and Define the Clinical Outcome

by Vittoria Disciglio, Giovanna Forte, Candida Fasano, Paola Sanese, Martina Lepore Signorile, Katia De Marco, Valentina Grossi, Filomena Cariola, Cristiano Simone
Published 2021-02-01

Clinical and functional characterization of a novel mutation in lamin a/c gene in a multigenerational family with arrhythmogenic cardiac laminopathy.

by Cinzia Forleo, Monica Carmosino, Nicoletta Resta, Alessandra Rampazzo, Rosanna Valecce, Sandro Sorrentino, Massimo Iacoviello, Francesco Pisani, Giuseppe Procino, Andrea Gerbino, Arnaldo Scardapane, Cristiano Simone, Martina Calore, Silvia Torretta, Maria Svelto, Stefano Favale
Published 2015-01-01

Spectrum of Germline Pathogenic Variants in BRCA1/2 Genes in the Apulian Southern Italy Population: Geographic Distribution and Evidence for Targeted Genetic Testing

by Margherita Patruno, Simona De Summa, Nicoletta Resta, Mariapia Caputo, Silvia Costanzo, Maria Digennaro, Brunella Pilato, Rosanna Bagnulo, Antonino Pantaleo, Cristiano Simone, Maria Iole Natalicchio, Elisabetta De Matteis, Paolo Tarantino, Stefania Tommasi, Angelo Paradiso
Published 2021-09-01

Molecular and Functional Characterization of Three Different Postzygotic Mutations in PIK3CA-Related Overgrowth Spectrum (PROS) Patients: Effects on PI3K/AKT/mTOR Signaling and Sen...

by Daria C Loconte, Valentina Grossi, Cristina Bozzao, Giovanna Forte, Rosanna Bagnulo, Alessandro Stella, Patrizia Lastella, Mario Cutrone, Francesco Benedicenti, Francesco C Susca, Margherita Patruno, Dora Varvara, Aldo Germani, Luciana Chessa, Nicola Laforgia, Romano Tenconi, Cristiano Simone, Nicoletta Resta
Published 2015-01-01

Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids

by Martina Lepore Signorile, Valentina Grossi, Simone Di Franco, Giovanna Forte, Vittoria Disciglio, Candida Fasano, Paola Sanese, Katia De Marco, Francesco Claudio Susca, Laura Rosa Mangiapane, Annalisa Nicotra, Gabriella Di Carlo, Francesco Dituri, Gianluigi Giannelli, Giuseppe Ingravallo, Gianluca Canettieri, Giorgio Stassi, Cristiano Simone
Published 2021-03-01

Targeting SMYD3 to Sensitize Homologous Recombination-Proficient Tumors to PARP-Mediated Synthetic Lethality

by Paola Sanese, Candida Fasano, Giacomo Buscemi, Cinzia Bottino, Silvia Corbetta, Edoardo Fabini, Valentina Silvestri, Virginia Valentini, Vittoria Disciglio, Giovanna Forte, Martina Lepore Signorile, Katia De Marco, Stefania Bertora, Valentina Grossi, Ummu Guven, Natale Porta, Valeria Di Maio, Elisabetta Manoni, Gianluigi Giannelli, Manuela Bartolini, Alberto Del Rio, Giuseppina Caretti, Laura Ottini, Cristiano Simone
Published 2020-10-01