Characterization and In Vivo Validation of a Three-Dimensional Multi-Cellular Culture Model to Study Heterotypic Interactions in Colorectal Cancer Cell Growth, Invasion and Metasta...

by Sarah Cattin, Laurent Ramont, Curzio Rüegg, Curzio Rüegg
Published 2018-07-01

The Crosstalk between FAK and Wnt Signaling Pathways in Cancer and Its Therapeutic Implication

by Janine Wörthmüller, Curzio Rüegg
Published 2020-11-01

MAGI1, a Scaffold Protein with Tumor Suppressive and Vascular Functions

by Janine Wörthmüller, Curzio Rüegg
Published 2021-06-01

Targeting the Extra-Cellular Matrix—Tumor Cell Crosstalk for Anti-Cancer Therapy: Emerging Alternatives to Integrin Inhibitors

by Girieca Lorusso, Curzio Rüegg, François Kuonen
Published 2020-07-01

Are Integrins Still Practicable Targets for Anti-Cancer Therapy?

by Begoña Alday-Parejo, Roger Stupp, Curzio Rüegg
Published 2019-07-01

The integrin antagonist cilengitide activates alphaVbeta3, disrupts VE-cadherin localization at cell junctions and enhances permeability in endothelial cells.

by Gian Carlo Alghisi, Lionel Ponsonnet, Curzio Rüegg
Published 2009-01-01

Breast Cancer Stem Cells with Tumor- versus Metastasis-Initiating Capacities Are Modulated by TGFBR1 Inhibition

by Flavia Fico, Mélanie Bousquenaud, Curzio Rüegg, Albert Santamaria-Martínez
Published 2019-07-01

Membrane-Interacting DNA Nanotubes Induce Cancer Cell Death

by Samet Kocabey, Aslihan Ekim Kocabey, Roger Schneiter, Curzio Rüegg
Published 2021-08-01

Dormant Tumor Cell Vaccination: A Mathematical Model of Immunological Dormancy in Triple-Negative Breast Cancer

by Reza Mehdizadeh, Seyed Peyman Shariatpanahi, Bahram Goliaei, Sanam Peyvandi, Curzio Rüegg
Published 2021-01-01

Radiotherapy suppresses angiogenesis in mice through TGF-betaRI/ALK5-dependent inhibition of endothelial cell sprouting.

by Natsuko Imaizumi, Yan Monnier, Monika Hegi, René-Olivier Mirimanoff, Curzio Rüegg
Published 2010-06-01

DNA Origami as Emerging Technology for the Engineering of Fluorescent and Plasmonic-Based Biosensors

by Morgane Loretan, Ivana Domljanovic, Mathias Lakatos, Curzio Rüegg, Guillermo P. Acuna
Published 2020-05-01

Obesity promotes the expansion of metastasis-initiating cells in breast cancer

by Mélanie Bousquenaud, Flavia Fico, Giovanni Solinas, Curzio Rüegg, Albert Santamaria-Martínez
Published 2018-09-01

Myeloid cells contribute to tumor lymphangiogenesis.

by Adrian Zumsteg, Vanessa Baeriswyl, Natsuko Imaizumi, Reto Schwendener, Curzio Rüegg, Gerhard Christofori
Published 2009-09-01

Emodin Inhibits Inflammation, Carcinogenesis, and Cancer Progression in the AOM/DSS Model of Colitis-Associated Intestinal Tumorigenesis

by Yunsha Zhang, Yunsha Zhang, Weiling Pu, Mélanie Bousquenaud, Sarah Cattin, Jelena Zaric, Li-kang Sun, Curzio Rüegg
Published 2021-01-01

MAGI1 localizes to mature focal adhesion and modulates endothelial cell adhesion, migration and angiogenesis

by Begoña Alday-Parejo, Kedar Ghimire, Oriana Coquoz, Gioele W. Albisetti, Luca Tamò, Jelena Zaric, Jimmy Stalin, Curzio Rüegg
Published 2021-01-01

Arginase inhibition suppresses lung metastasis in the 4T1 breast cancer model independently of the immunomodulatory and anti-metastatic effects of VEGFR-2 blockade

by Chiara Secondini, Oriana Coquoz, Lorenzo Spagnuolo, Thibaud Spinetti, Sanam Peyvandi, Laura Ciarloni, Francesca Botta, Carole Bourquin, Curzio Rüegg
Published 2017-06-01

Discovery of a 29-gene panel in peripheral blood mononuclear cells for the detection of colorectal cancer and adenomas using high throughput real-time PCR.

by Laura Ciarloni, Sahar Hosseinian, Sylvain Monnier-Benoit, Natsuko Imaizumi, Gian Dorta, Curzio Ruegg, DGNP-COL-0310 Study Group
Published 2015-01-01

MAGI1, a New Potential Tumor Suppressor Gene in Estrogen Receptor Positive Breast Cancer

by Begoña Alday-Parejo, François Richard, Janine Wörthmüller, Tilman Rau, José A. Galván, Christine Desmedt, Albert Santamaria-Martinez, Curzio Rüegg
Published 2020-01-01

MAGI1 Mediates eNOS Activation and NO Production in Endothelial Cells in Response to Fluid Shear Stress

by Kedar Ghimire, Jelena Zaric, Begoña Alday-Parejo, Jochen Seebach, Mélanie Bousquenaud, Jimmy Stalin, Grégory Bieler, Hans-Joachim Schnittler, Curzio Rüegg
Published 2019-04-01

Modulation of angiogenic and inflammatory response in glioblastoma by hypoxia.

by Anastasia Murat, Eugenia Migliavacca, S Farzana Hussain, Amy B Heimberger, Isabelle Desbaillets, Marie-France Hamou, Curzio Rüegg, Roger Stupp, Mauro Delorenzi, Monika E Hegi
Published 2009-06-01