Harnessing the protective potential of HIV-1 neutralizing antibodies [version 1; referees: 2 approved]

by S Abigail Smith, Cynthia A Derdeyn
Published 2016-01-01

VH1-69 Utilizing Antibodies Are Capable of Mediating Non-neutralizing Fc-Mediated Effector Functions Against the Transmitted/Founder gp120

by S. Abigail Smith, S. Abigail Smith, Samantha L. Burton, Samantha L. Burton, William Kilembe, Shabir Lakhi, Etienne Karita, Matt Price, Matt Price, Susan Allen, Cynthia A. Derdeyn, Cynthia A. Derdeyn, Cynthia A. Derdeyn
Published 2019-01-01

A mechanistic understanding of allosteric immune escape pathways in the HIV-1 envelope glycoprotein.

by Anurag Sethi, Jianhui Tian, Cynthia A Derdeyn, Bette Korber, S Gnanakaran
Published 2013-01-01

Effect of Glycosylation on an Immunodominant Region in the V1V2 Variable Domain of the HIV-1 Envelope gp120 Protein.

by Jianhui Tian, Cesar A López, Cynthia A Derdeyn, Morris S Jones, Abraham Pinter, Bette Korber, S Gnanakaran
Published 2016-10-01

Diversification in the HIV-1 Envelope Hyper-variable Domains V2, V4, and V5 and Higher Probability of Transmitted/Founder Envelope Glycosylation Favor the Development of Heterologo...

by S Abigail Smith, Samantha L Burton, William Kilembe, Shabir Lakhi, Etienne Karita, Matt Price, Susan Allen, Eric Hunter, Cynthia A Derdeyn
Published 2016-11-01

Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways.

by Rong Rong, Bing Li, Rebecca M Lynch, Richard E Haaland, Megan K Murphy, Joseph Mulenga, Susan A Allen, Abraham Pinter, George M Shaw, Eric Hunter, James E Robinson, S Gnanakaran, Cynthia A Derdeyn
Published 2009-09-01

Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1.

by Richard E Haaland, Paulina A Hawkins, Jesus Salazar-Gonzalez, Amber Johnson, Amanda Tichacek, Etienne Karita, Olivier Manigart, Joseph Mulenga, Brandon F Keele, George M Shaw, Beatrice H Hahn, Susan A Allen, Cynthia A Derdeyn, Eric Hunter
Published 2009-01-01

Viral escape from neutralizing antibodies in early subtype A HIV-1 infection drives an increase in autologous neutralization breadth.

by Megan K Murphy, Ling Yue, Ruimin Pan, Saikat Boliar, Anurag Sethi, Jianhui Tian, Katja Pfafferot, Etienne Karita, Susan A Allen, Emmanuel Cormier, Paul A Goepfert, Persephone Borrow, James E Robinson, S Gnanakaran, Eric Hunter, Xiang-Peng Kong, Cynthia A Derdeyn
Published 2013-02-01

The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection.

by Tysheena P Charles, Samantha L Burton, Prabhu S Arunachalam, Christopher A Cottrell, Leigh M Sewall, Venkata S Bollimpelli, Sailaja Gangadhara, Antu K Dey, Andrew B Ward, George M Shaw, Eric Hunter, Rama R Amara, Bali Pulendran, Marit J van Gils, Cynthia A Derdeyn
Published 2021-02-01

A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo.

by Nadeene E Riddick, Emilia A Hermann, Lamorris M Loftin, Sarah T Elliott, Winston C Wey, Barbara Cervasi, Jessica Taaffe, Jessica C Engram, Bing Li, James G Else, Yingying Li, Beatrice H Hahn, Cynthia A Derdeyn, Donald L Sodora, Cristian Apetrei, Mirko Paiardini, Guido Silvestri, Ronald G Collman
Published 2010-08-01

Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques.

by Ann Chahroudi, Emily Cartwright, S Thera Lee, Maud Mavigner, Diane G Carnathan, Benton Lawson, Paul M Carnathan, Tayebeh Hashempoor, Megan K Murphy, Tracy Meeker, Stephanie Ehnert, Christopher Souder, James G Else, Joyce Cohen, Ronald G Collman, Thomas H Vanderford, Sallie R Permar, Cynthia A Derdeyn, Francois Villinger, Guido Silvestri
Published 2014-03-01

CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells.

by Luca Micci, Xavier Alvarez, Robin I Iriele, Alexandra M Ortiz, Emily S Ryan, Colleen S McGary, Claire Deleage, Brigitte B McAtee, Tianyu He, Cristian Apetrei, Kirk Easley, Savita Pahwa, Ronald G Collman, Cynthia A Derdeyn, Miles P Davenport, Jacob D Estes, Guido Silvestri, Andrew A Lackner, Mirko Paiardini
Published 2014-10-01

Role of transmitted Gag CTL polymorphisms in defining replicative capacity and early HIV-1 pathogenesis.

by Jessica L Prince, Daniel T Claiborne, Jonathan M Carlson, Malinda Schaefer, Tianwei Yu, Shabir Lahki, Heather A Prentice, Ling Yue, Sundaram A Vishwanathan, William Kilembe, Paul Goepfert, Matthew A Price, Jill Gilmour, Joseph Mulenga, Paul Farmer, Cynthia A Derdeyn, Jiaming Tang, David Heckerman, Richard A Kaslow, Susan A Allen, Eric Hunter
Published 2012-01-01

Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients.

by Ling Yue, Katja J Pfafferott, Joshua Baalwa, Karen Conrod, Catherine C Dong, Cecilia Chui, Rong Rong, Daniel T Claiborne, Jessica L Prince, Jianming Tang, Ruy M Ribeiro, Emmanuel Cormier, Beatrice H Hahn, Alan S Perelson, George M Shaw, Etienne Karita, Jill Gilmour, Paul Goepfert, Cynthia A Derdeyn, Susan A Allen, Persephone Borrow, Eric Hunter
Published 2015-01-01