Experimental reconstitution of chronic ER stress in the liver reveals feedback suppression of BiP mRNA expression

by Javier A Gomez, D Thomas Rutkowski
Published 2016-12-01

Temporal clustering of gene expression links the metabolic transcription factor HNF4α to the ER stress-dependent gene regulatory network

by Angela M Arensdorf, Diane eDeZwaan McCabe, Randal J Kaufman, D Thomas Rutkowski
Published 2013-09-01

piggyBac-mediated phenotypic correction of factor VIII deficiency

by Janice M Staber, Molly J Pollpeter, Angela Arensdorf, Patrick L Sinn, D Thomas Rutkowski, Paul B McCray, Jr
Published 2014-01-01

The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis.

by Diane DeZwaan-McCabe, Jesse D Riordan, Angela M Arensdorf, Michael S Icardi, Adam J Dupuy, D Thomas Rutkowski
Published 2013-01-01

NADPH and Glutathione Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis

by Erica R. Gansemer, Kyle S. McCommis, Michael Martino, Abdul Qaadir King-McAlpin, Matthew J. Potthoff, Brian N. Finck, Eric B. Taylor, D. Thomas Rutkowski
Published 2020-05-01

Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins.

by D Thomas Rutkowski, Stacey M Arnold, Corey N Miller, Jun Wu, Jack Li, Kathryn M Gunnison, Kazutoshi Mori, Amir A Sadighi Akha, David Raden, Randal J Kaufman
Published 2006-11-01

ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis

by Diane DeZwaan-McCabe, Ryan D. Sheldon, Michelle C. Gorecki, Deng-Fu Guo, Erica R. Gansemer, Randal J. Kaufman, Kamal Rahmouni, Matthew P. Gillum, Eric B. Taylor, Lynn M. Teesch, D. Thomas Rutkowski
Published 2017-05-01