PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

by Shota Tanaka, Tracy T. Batchelor, A. John Iafrate, Dora Dias-Santagata, Darrell R. Borger, Leif W. Ellisen, Daniel Yang, David N. Louis, Daniel P. Cahill, Andrew S. Chi
Published 2019-04-01

Synergistic effects of targeted PI3K signaling inhibition and chemotherapy in liposarcoma.

by Shang Guo, Hector Lopez-Marquez, Kenneth C Fan, Edwin Choy, Gregory Cote, David Harmon, G Petur Nielsen, Cao Yang, Changqing Zhang, Henry Mankin, Francis J Hornicek, Darrell R Borger, Zhenfeng Duan
Published 2014-01-01

BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications.

by Dora Dias-Santagata, Quynh Lam, Kathy Vernovsky, Natalie Vena, Jochen K Lennerz, Darrell R Borger, Tracy T Batchelor, Keith L Ligon, A John Iafrate, Azra H Ligon, David N Louis, Sandro Santagata
Published 2011-03-01

Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model.

by Christopher K McCann, Whitfield B Growdon, Kashmira Kulkarni-Datar, Michael D Curley, Anne M Friel, Jennifer L Proctor, Hana Sheikh, Igor Deyneko, Jeanne A Ferguson, Vinod Vathipadiekal, Michael J Birrer, Darrell R Borger, Gayatry Mohapatra, Lawrence R Zukerberg, Rosemary Foster, John R Macdougall, Bo R Rueda
Published 2011-01-01

Primary tumor sidedness is an independent prognostic marker for survival in metastatic colorectal cancer: Results from a large retrospective cohort with mutational analysis

by Sophia C. Kamran, Jeffrey W. Clark, Hui Zheng, Darrell R. Borger, Lawrence S. Blaszkowsky, Jill N. Allen, Eunice L. Kwak, Jennifer Y. Wo, Aparna R. Parikh, Ryan D. Nipp, Janet E. Murphy, Lipika Goyal, Andrew X. Zhu, A. John Iafrate, Ryan B. Corcoran, David P. Ryan, Theodore S. Hong
Published 2018-07-01