Regulation of T cells by their environment

by Anne L Astier, David A. Hafler
Published 2015-05-01

Class II MHC self-antigen presentation in human B and T lymphocytes.

by Cristina Maria Costantino, Eric Spooner, Hidde L Ploegh, David A Hafler
Published 2012-01-01

Investigating the antigen specificity of multiple sclerosis central nervous system-derived immunoglobulins

by Simon N Willis, Simon N Willis, Simon N Willis, Panos eStathopoulos, Anne eChastre, Shannon D. Compton, David A. Hafler, David A. Hafler, Kevin C O'Connor
Published 2015-11-01

NEBULA is a fast negative binomial mixed model for differential or co-expression analysis of large-scale multi-subject single-cell data

by Liang He, Jose Davila-Velderrain, Tomokazu S. Sumida, David A. Hafler, Manolis Kellis, Alexander M. Kulminski
Published 2021-05-01

CXCR3+ T cells in multiple sclerosis correlate with reduced diversity of the gut microbiome

by Siobhán Ní Choileáin, Markus Kleinewietfeld, Khadir Raddassi, David A. Hafler, William E. Ruff, Erin E. Longbrake
Published 2020-01-01

Comprehensive Phenotyping in Multiple Sclerosis: Discovery Based Proteomics and the Current Understanding of Putative Biomarkers

by Kevin C. O’Connor, Sushmita Mimi Roy, Christopher H. Becker, David A. Hafler, Aaron B. Kantor
Published 2006-01-01

From Big Data to Precision Medicine

by Tim Hulsen, Saumya S. Jamuar, Alan R. Moody, Jason H. Karnes, Orsolya Varga, Stine Hedensted, Roberto Spreafico, David A. Hafler, Eoin F. McKinney
Published 2019-03-01

Functional differences between PD-1+ and PD-1- CD4+ effector T cells in healthy donors and patients with glioblastoma multiforme.

by Brittany A Goods, Amanda L Hernandez, Daniel E Lowther, Liliana E Lucca, Benjamin A Lerner, Murat Gunel, Khadir Raddassi, Vlad Coric, David A Hafler, J Christopher Love
Published 2017-01-01

Enhanced astrocyte responses are driven by a genetic risk allele associated with multiple sclerosis

by Gerald Ponath, Matthew R. Lincoln, Maya Levine-Ritterman, Calvin Park, Somiah Dahlawi, Mayyan Mubarak, Tomokazu Sumida, Laura Airas, Shun Zhang, Cigdem Isitan, Thanh D. Nguyen, Cedric S. Raine, David A. Hafler, David Pitt
Published 2018-12-01

Two genetic variants explain the association of European ancestry with multiple sclerosis risk in African-Americans

by Nathan Nakatsuka, Nick Patterson, Nikolaos A. Patsopoulos, Nicolas Altemose, Arti Tandon, Ashley H. Beecham, Jacob L. McCauley, Noriko Isobe, Stephen Hauser, Philip L. De Jager, David A. Hafler, Jorge R. Oksenberg, David Reich
Published 2020-10-01

Microbial reprogramming inhibits Western diet-associated obesity.

by Theofilos Poutahidis, Markus Kleinewietfeld, Christopher Smillie, Tatiana Levkovich, Alison Perrotta, Siddheshvar Bhela, Bernard J Varian, Yassin M Ibrahim, Jessica R Lakritz, Sean M Kearney, Antonis Chatzigiagkos, David A Hafler, Eric J Alm, Susan E Erdman
Published 2013-01-01

Clinical Significance of PDCD4 in Melanoma by Subcellular Expression and in Tumor-Associated Immune Cells

by Thuy T. Tran, Chetan K. Rane, Christopher R. Zito, Sarah A. Weiss, Shlomit Jessel, Liliana Lucca, Benjamin Y. Lu, Victor O. Oria, Adebowale Adeniran, Veronica L. Chiang, Sacit Bulent Omay, David A. Hafler, Harriet M. Kluger, Lucia B. Jilaveanu
Published 2021-03-01

Genome-wide assessment for genetic variants associated with ventricular dysfunction after primary coronary artery bypass graft surgery.

by Amanda A Fox, Mias Pretorius, Kuang-Yu Liu, Charles D Collard, Tjorvi E Perry, Stanton K Shernan, Philip L De Jager, David A Hafler, Daniel S Herman, Steven R DePalma, Dan M Roden, Jochen D Muehlschlegel, Brian S Donahue, Dawood Darbar, J G Seidman, Simon C Body, Christine E Seidman
Published 2011-01-01

Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects.

by Nikolaos A Patsopoulos, Lisa F Barcellos, Rogier Q Hintzen, Catherine Schaefer, Cornelia M van Duijn, Janelle A Noble, Towfique Raj, IMSGC, ANZgene, Pierre-Antoine Gourraud, Barbara E Stranger, Jorge Oksenberg, Tomas Olsson, Bruce V Taylor, Stephen Sawcer, David A Hafler, Mary Carrington, Philip L De Jager, Paul I W de Bakker
Published 2013-11-01

IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.

by Lisa M Maier, Christopher E Lowe, Jason Cooper, Kate Downes, David E Anderson, Christopher Severson, Pamela M Clark, Brian Healy, Neil Walker, Cristin Aubin, Jorge R Oksenberg, Stephen L Hauser, Alistair Compston, Stephen Sawcer, International Multiple Sclerosis Genetics Consortium, Philip L De Jager, Linda S Wicker, John A Todd, David A Hafler
Published 2009-01-01

A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01.

by Bruce A C Cree, John D Rioux, Jacob L McCauley, Pierre-Antoine F D Gourraud, Philippe Goyette, Joseph McElroy, Philip De Jager, Adam Santaniello, Timothy J Vyse, Peter K Gregersen, Daniel Mirel, David A Hafler, Jonathan L Haines, Margaret A Pericak-Vance, Alastair Compston, Stephen J Sawcer, Jorge R Oksenberg, Stephen L Hauser, IMAGEN, IMSGC
Published 2010-06-01

Pervasive sharing of genetic effects in autoimmune disease.

by Chris Cotsapas, Benjamin F Voight, Elizabeth Rossin, Kasper Lage, Benjamin M Neale, Chris Wallace, Gonçalo R Abecasis, Jeffrey C Barrett, Timothy Behrens, Judy Cho, Philip L De Jager, James T Elder, Robert R Graham, Peter Gregersen, Lars Klareskog, Katherine A Siminovitch, David A van Heel, Cisca Wijmenga, Jane Worthington, John A Todd, David A Hafler, Stephen S Rich, Mark J Daly, FOCiS Network of Consortia
Published 2011-08-01

Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patientsResearch in context

by Judith A. James, Hua Chen, Kendra A. Young, Elizabeth A. Bemis, Jennifer Seifert, Rebecka L. Bourn, Kevin D. Deane, M. Kristen Demoruelle, Marie Feser, James R. O'Dell, Michael H. Weisman, Richard M. Keating, Patrick M. Gaffney, Jennifer A. Kelly, Carl D. Langefeld, John B. Harley, William Robinson, David A. Hafler, Kevin C. O'Connor, Jane Buckner, Joel M. Guthridge, Jill M. Norris, V. Michael Holers
Published 2019-04-01

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

by Anke Fuchs, Mateusz Gliwiński, Nathali Grageda, Rachel Spiering, Abul K. Abbas, Silke Appel, Rosa Bacchetta, Manuela Battaglia, David Berglund, Bruce Blazar, Jeffrey A. Bluestone, Martin Bornhäuser, Anja ten Brinke, Todd M. Brusko, Nathalie Cools, Maria Cristina Cuturi, Edward Geissler, Nick Giannoukakis, Karolina Gołab, David A. Hafler, S. Marieke van Ham, Joanna Hester, Keli Hippen, Mauro Di Ianni, Natasa Ilic, John Isaacs, John Isaacs, Fadi Issa, Dorota Iwaszkiewicz-Grześ, Elmar Jaeckel, Irma Joosten, David Klatzmann, Hans Koenen, Cees van Kooten, Olle Korsgren, Olle Korsgren, Karsten Kretschmer, Karsten Kretschmer, Megan Levings, Natalia Maria Marek-Trzonkowska, Marc Martinez-Llordella, Djordje Miljkovic, Kingston H.G. Mills, Joana P. Miranda, Ciriaco A. Piccirillo, Amy L. Putnam, Thomas Ritter, Maria Grazia Roncarolo, Shimon Sakaguchi, Silvia Sánchez-Ramón, Birgit Sawitzki, Ljiljana Sofronic-Milosavljevic, Megan Sykes, Qizhi Tang, Marta Vives-Pi, Herman Waldmann, Piotr Witkowski, Kathryn J. Wood, Silvia Gregori, Catharien M. U. Hilkens, Giovanna Lombardi, Phillip Lord, Eva M. Martinez-Caceres, Piotr Trzonkowski
Published 2018-01-01