Fishing for prion protein function.

by Roberto Chiesa, David A Harris
Published 2009-03-01

Aβ receptors specifically recognize molecular features displayed by fibril ends and neurotoxic oligomers

by Ladan Amin, David A. Harris
Published 2021-06-01

Prion Diseases: What Is the Neurotoxic Molecule?

by Roberto Chiesa, David A. Harris
Published 2001-10-01

GFP-tagged prion protein is correctly localized and functionally active in the brains of transgenic mice

by Sami Barmada, Pedro Piccardo, Keiji Yamaguchi, Bernardino Ghetti, David A Harris
Published 2004-08-01

GFP-tagged mutant prion protein forms intra-axonal aggregates in transgenic mice

by Andrea Z. Medrano, Sami J. Barmada, Emiliano Biasini, David A. Harris
Published 2008-07-01

A Neuronal Culture System to Detect Prion Synaptotoxicity.

by Cheng Fang, Thibaut Imberdis, Maria Carmen Garza, Holger Wille, David A Harris
Published 2016-05-01

The N-terminal, polybasic region is critical for prion protein neuroprotective activity.

by Jessie A Turnbaugh, Laura Westergard, Ursula Unterberger, Emiliano Biasini, David A Harris
Published 2011-01-01

Prions activate a p38 MAPK synaptotoxic signaling pathway.

by Cheng Fang, Bei Wu, Nhat T T Le, Thibaut Imberdis, Robert C C Mercer, David A Harris
Published 2018-09-01

Immunopurification of pathological prion protein aggregates.

by Emiliano Biasini, Laura Tapella, Susanna Mantovani, Matteo Stravalaci, Marco Gobbi, David A Harris, Roberto Chiesa
Published 2009-11-01

Structural Features of Heparin and Its Interactions With Cellular Prion Protein Measured by Surface Plasmon Resonance

by So Young Kim, So Young Kim, Fuming Zhang, David A. Harris, Robert J. Linhardt, Robert J. Linhardt
Published 2020-11-01

Primary Myopathy and Accumulation of PrPSc-Like Molecules in Peripheral Tissues of Transgenic Mice Expressing a Prion Protein Insertional Mutation

by Roberto Chiesa, Alan Pestronk, Robert E. Schmidt, Warren G. Tourtellotte, Bernardino Ghetti, Pedro Piccardo, David A. Harris
Published 2001-04-01

The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells.

by Emiliano Biasini, Jessie A Turnbaugh, Tania Massignan, Pietro Veglianese, Gianluigi Forloni, Valentina Bonetto, Roberto Chiesa, David A Harris
Published 2012-01-01

The N-terminus of the prion protein is a toxic effector regulated by the C-terminus

by Bei Wu, Alex J McDonald, Kathleen Markham, Celeste B Rich, Kyle P McHugh, Jörg Tatzelt, David W Colby, Glenn L Millhauser, David A Harris
Published 2017-05-01