Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice.

by Susie Lee, Lawrence A Donehower, Alan J Herron, David D Moore, Loning Fu
Published 2010-06-01

Circadian dysregulation disrupts bile acid homeostasis.

by Ke Ma, Rui Xiao, Hsiu-Ting Tseng, Lu Shan, Loning Fu, David D Moore
Published 2009-08-01

Bile Acids Activate YAP to Promote Liver Carcinogenesis

by Sayeepriyadarshini Anakk, Manoj Bhosale, Valentina A. Schmidt, Randy L. Johnson, Milton J. Finegold, David D. Moore
Published 2013-11-01

Eating Pattern and Nutritional Risks among People with Multiple Sclerosis Following a Modified Paleolithic Diet

by Tyler J. Titcomb, Babita Bisht, David D. Moore, Yashpal S. Chhonker, Daryl J. Murry, Linda G. Snetselaar, Terry L. Wahls
Published 2020-06-01

LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival

by James R. Bayrer, Hongtao Wang, Roy Nattiv, Miyuki Suzawa, Hazel S. Escusa, Robert J. Fletterick, Ophir D. Klein, David D. Moore, Holly A. Ingraham
Published 2018-10-01

Activation of the constitutive androstane receptor decreases HDL in wild-type and human apoA-I transgenic mice

by David Masson, Mohamed Qatanani, Anne Laure Sberna, Rui Xiao, Jean Paul Pais de Barros, Jacques Grober, Valerie Deckert, Anne Athias, Philippe Gambert, Laurent Lagrost, David D. Moore, Mahfoud Assem
Published 2008-08-01

Correction: Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution

by Jennifer L Mamrosh, Jae Man Lee, Martin Wagner, Peter J Stambrook, Richard J Whitby, Richard N Sifers, San-Pin Wu, Ming-Jer Tsai, Francesco J DeMayo, David D Moore
Published 2015-07-01

Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution

by Jennifer L Mamrosh, Jae Man Lee, Martin Wagner, Peter J Stambrook, Richard J Whitby, Richard N Sifers, San-Pin Wu, Ming-Jer Tsai, Francesco J DeMayo, David D Moore
Published 2014-04-01

Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice.

by Ramiya Kumar, Linda C Mota, Elizabeth J Litoff, John P Rooney, W Tyler Boswell, Elliott Courter, Charles M Henderson, Juan P Hernandez, J Christopher Corton, David D Moore, William S Baldwin
Published 2017-01-01

Thyroid Hormone Regulates the mRNA Expression of Small Heterodimer Partner through Liver Receptor Homolog-1

by Hwa Young Ahn, Hwan Hee Kim, Ye An Kim, Min Kim, Jung Hun Ohn, Sung Soo Chung, Yoon-Kwang Lee, Do Joon Park, Kyong Soo Park, David D. Moore, Young Joo Park
Published 2015-12-01

A Versatile Tumor Gene Deletion System Reveals a Crucial Role for FGFR1 in Breast Cancer Metastasis

by Wei Wang, Yanling Meng, Bingning Dong, Jie Dong, Michael M. Ittmann, Chad J. Creighton, Yang Lu, Hong Zhang, Tao Shen, Jianghua Wang, David R. Rowley, Yi Li, Fengju Chen, David D. Moore, Feng Yang
Published 2017-05-01

Ube2i deletion in adipocytes causes lipoatrophy in mice

by Aaron R. Cox, Natasha Chernis, Kang Ho Kim, Peter M. Masschelin, Pradip K. Saha, Shawn M. Briley, Robert Sharp, Xin Li, Jessica B. Felix, Zheng Sun, David D. Moore, Stephanie A. Pangas, Sean M. Hartig
Published 2021-06-01

Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partner

by Young Joo Park, Seong Chul Kim, Jeehee Kim, Sayeepriyadarshini Anakk, Jae Man Lee, Hsiu-Ting Tseng, Vijay Yechoor, Junchol Park, June-Seek Choi, Hak Chul Jang, Ki-Up Lee, Colleen M. Novak, David D. Moore, Yoon Kwang Lee
Published 2011-12-01

TFEB regulates murine liver cell fate during development and regeneration

by Nunzia Pastore, Tuong Huynh, Niculin J. Herz, Alessia Calcagni’, Tiemo J. Klisch, Lorenzo Brunetti, Kangho Ho Kim, Marco De Giorgi, Ayrea Hurley, Annamaria Carissimo, Margherita Mutarelli, Niya Aleksieva, Luca D’Orsi, William R. Lagor, David D. Moore, Carmine Settembre, Milton J. Finegold, Stuart J. Forbes, Andrea Ballabio
Published 2020-05-01

A human liver chimeric mouse model for non-alcoholic fatty liver disease

by Beatrice Bissig-Choisat, Michele Alves-Bezerra, Barry Zorman, Scott A. Ochsner, Mercedes Barzi, Xavier Legras, Diane Yang, Malgorzata Borowiak, Adam M. Dean, Robert B. York, N. Thao N. Galvan, John Goss, William R. Lagor, David D. Moore, David E. Cohen, Neil J. McKenna, Pavel Sumazin, Karl-Dimiter Bissig
Published 2021-06-01

Epigenome environment interactions accelerate epigenomic aging and unlock metabolically restricted epigenetic reprogramming in adulthood

by Lindsey S. Treviño, Jianrong Dong, Ahkilesh Kaushal, Tiffany A. Katz, Rahul Kumar Jangid, Matthew J. Robertson, Sandra L. Grimm, Chandra Shekar R. Ambati, Vasanta Putluri, Aaron R. Cox, Kang Ho Kim, Thaddeus D. May, Morgan R. Gallo, David D. Moore, Sean M. Hartig, Charles E. Foulds, Nagireddy Putluri, Cristian Coarfa, Cheryl Lyn Walker
Published 2020-05-01

Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis

by Natalia Gomez-Ospina, Carol J. Potter, Rui Xiao, Kandamurugu Manickam, Mi-Sun Kim, Kang Ho Kim, Benjamin L. Shneider, Jennifer L. Picarsic, Theodora A. Jacobson, Jing Zhang, Weimin He, Pengfei Liu, A. S. Knisely, Milton J. Finegold, Donna M. Muzny, Eric Boerwinkle, James R. Lupski, Sharon E. Plon, Richard A. Gibbs, Christine M. Eng, Yaping Yang, Gabriel C. Washington, Matthew H. Porteus, William E. Berquist, Neeraja Kambham, Ravinder J. Singh, Fan Xia, Gregory M. Enns, David D. Moore
Published 2016-02-01