Atomic-level characterization of the activation mechanism of SERCA by calcium.

by L Michel Espinoza-Fonseca, David D Thomas
Published 2011-01-01

Actin-Myosin Interaction: Structure, Function and Drug Discovery

by Piyali Guhathakurta, Ewa Prochniewicz, David D. Thomas
Published 2018-09-01

Enhanced synaptotagmin plasticity derived from pairing intrinsic disorder with synaptic vesicle lipids

by Michael E. Fealey, David D. Thomas, Anne Hinderliter
Published 2017-07-01

Microsecond molecular dynamics simulations of Mg²⁺- and K⁺-bound E1 intermediate states of the calcium pump.

by L Michel Espinoza-Fonseca, Joseph M Autry, David D Thomas
Published 2014-01-01

Structural dynamics of calmodulin-ryanodine receptor interactions: electron paramagnetic resonance using stereospecific spin labels

by Cheng Her, Andrew R. Thompson, Christine B. Karim, David D. Thomas
Published 2018-07-01

Age affects myosin relaxation states in skeletal muscle fibers of female but not male mice.

by Lien A Phung, Sira M Karvinen, Brett A Colson, David D Thomas, Dawn A Lowe
Published 2018-01-01

2-Color calcium pump reveals closure of the cytoplasmic headpiece with calcium binding.

by Zhanjia Hou, Zhihong Hu, Daniel J Blackwell, Tyler D Miller, David D Thomas, Seth L Robia
Published 2012-01-01

Met125 is essential for maintaining the structural integrity of calmodulin’s C-terminal domain

by Sarah E. D. Nelson, Daniel K. Weber, Robyn T. Rebbeck, Razvan L. Cornea, Gianluigi Veglia, David D. Thomas
Published 2020-12-01

The functional significance of redox-mediated intersubunit cross-linking in regulation of human type 2 ryanodine receptor

by Roman Nikolaienko, Elisa Bovo, Robyn T. Rebbeck, Daniel Kahn, David D. Thomas, Razvan L. Cornea, Aleksey V. Zima
Published 2020-10-01

Calcium Stimulates Self-Assembly of Protein Kinase C α In Vitro.

by Carter J Swanson, Ruth F Sommese, Karl J Petersen, Michael Ritt, Joshua Karslake, David D Thomas, Sivaraj Sivaramakrishnan
Published 2016-01-01

Structural basis for high-affinity actin binding revealed by a β-III-spectrin SCA5 missense mutation

by Adam W. Avery, Michael E. Fealey, Fengbin Wang, Albina Orlova, Andrew R. Thompson, David D. Thomas, Thomas S. Hays, Edward H. Egelman
Published 2017-11-01

Sarcolipin Exhibits Abundant RNA Transcription and Minimal Protein Expression in Horse Gluteal Muscle

by Joseph M. Autry, Christine B. Karim, Sudeep Perumbakkam, Carrie J. Finno, Erica C. McKenzie, David D. Thomas, Stephanie J. Valberg
Published 2020-11-01

Live-Cell Cardiac-Specific High-Throughput Screening Platform for Drug-Like Molecules that Enhance Ca²⁺Transport

by Tory M. Schaaf, Evan Kleinboehl, Samantha L. Yuen, Lauren N. Roelike, Bengt Svensson, Andrew R. Thompson, Razvan L. Cornea, David D. Thomas
Published 2020-05-01

Red-Shifted FRET Biosensors for High-Throughput Fluorescence Lifetime Screening

by Tory M. Schaaf, Ang Li, Benjamin D. Grant, Kurt Peterson, Samantha Yuen, Prachi Bawaskar, Evan Kleinboehl, Ji Li, David D. Thomas, Gregory D. Gillispie
Published 2018-10-01

Mechanical factors tune the sensitivity of mdx muscle to eccentric strength loss and its protection by antioxidant and calcium modulators

by Angus Lindsay, Cory W. Baumann, Robyn T. Rebbeck, Samantha L. Yuen, William M. Southern, James S. Hodges, Razvan L. Cornea, David D. Thomas, James M. Ervasti, Dawn A. Lowe
Published 2020-02-01

Structural basis for allosteric control of the SERCA-Phospholamban membrane complex by Ca2+ and phosphorylation

by Daniel K Weber, U Venkateswara Reddy, Songlin Wang, Erik K Larsen, Tata Gopinath, Martin B Gustavsson, Razvan L Cornea, David D Thomas, Alfonso De Simone, Gianluigi Veglia
Published 2021-05-01

Defective internal allosteric network imparts dysfunctional ATP/substrate-binding cooperativity in oncogenic chimera of protein kinase A

by Cristina Olivieri, Caitlin Walker, Adak Karamafrooz, Yingjie Wang, V. S. Manu, Fernando Porcelli, Donald K. Blumenthal, David D. Thomas, David A. Bernlohr, Simon M. Sandford, Susan S. Taylor, Gianluigi Veglia
Published 2021-03-01

Author Correction: Defective internal allosteric network imparts dysfunctional ATP/substrate-binding cooperativity in oncogenic chimera of protein kinase A

by Cristina Olivieri, Caitlin Walker, Adak Karamafrooz, Yingjie Wang, V. S. Manu, Fernando Porcelli, Donald K. Blumenthal, David D. Thomas, David A. Bernlohr, Sanford M. Simon, Susan S. Taylor, Gianluigi Veglia
Published 2021-04-01

A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation

by Emily F Ruff, Joseph M Muretta, Andrew R Thompson, Eric W Lake, Soreen Cyphers, Steven K Albanese, Sonya M Hanson, Julie M Behr, David D Thomas, John D Chodera, Nicholas M Levinson
Published 2018-02-01

Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors

by Anthony R. Braun, Elly E. Liao, Mian Horvath, Prakriti Kalra, Karen Acosta, Malaney C. Young, Noah Nathan Kochen, Chih Hung Lo, Roland Brown, Michael D. Evans, William C. K. Pomerantz, Elizabeth Rhoades, Kelvin Luk, Razvan L. Cornea, David D. Thomas, Jonathan N. Sachs
Published 2021-06-01