A binding cooperativity switch driven by synergistic structural swelling of an osmo-regulatory protein pair

by Abhishek Narayan, Soundhararajan Gopi, David Fushman, Athi N. Naganathan
Published 2019-04-01

Base-CP proteasome can serve as a platform for stepwise lid formation

by Zanlin Yu, Nurit Livnat‑Levanon, Oded Kleifeld, Wissam Mansour, Mark A. Nakasone, Carlos A. Castaneda, Emma K. Dixon, David Fushman, Noa Reis, Elah Pick, Michael H. Glickman
Published 2015-05-01

Perturbing the ubiquitin pathway reveals how mitosis is hijacked to denucleate and regulate cell proliferation and differentiation in vivo.

by Andrea Caceres, Fu Shang, Eric Wawrousek, Qing Liu, Orna Avidan, Ales Cvekl, Ying Yang, Aydin Haririnia, Andrew Storaska, David Fushman, Jer Kuszak, Edward Dudek, Donald Smith, Allen Taylor
Published 2010-10-01

Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain

by Helge M. Magnussen, Syed F. Ahmed, Gary. J. Sibbet, Ventzislava A. Hristova, Koji Nomura, Andreas K. Hock, Lewis J. Archibald, Andrew G. Jamieson, David Fushman, Karen H. Vousden, Allan M. Weissman, Danny T. Huang
Published 2020-04-01