Bitter taste stimuli induce differential neural codes in mouse brain.

by David M Wilson, John D Boughter, Christian H Lemon
Published 2012-01-01

Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice.

by Agathi-Vassiliki Goula, Brian R Berquist, David M Wilson, Vanessa C Wheeler, Yvon Trottier, Karine Merienne
Published 2009-12-01

Altered endoribonuclease activity of apurinic/apyrimidinic endonuclease 1 variants identified in the human population.

by Wan Cheol Kim, Conan Ma, Wai-Ming Li, Manbir Chohan, David M Wilson, Chow H Lee
Published 2014-01-01

Diverse small molecule inhibitors of human apurinic/apyrimidinic endonuclease APE1 identified from a screen of a large public collection.

by Dorjbal Dorjsuren, Daemyung Kim, Vaddadi N Vyjayanti, David J Maloney, Ajit Jadhav, David M Wilson, Anton Simeonov
Published 2012-01-01

Identification and quantification of DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) in human cells by liquid chromatography/isotope-dilution tandem mass spectrometr...

by Güldal Kirkali, Pawel Jaruga, Prasad T Reddy, Alessandro Tona, Bryant C Nelson, Mengxia Li, David M Wilson, Miral Dizdaroglu
Published 2013-01-01

Functional assessment of population and tumor-associated APE1 protein variants.

by Jennifer L Illuzzi, Nicole A Harris, Brittney A Manvilla, Daemyung Kim, Mengxia Li, Alexander C Drohat, David M Wilson
Published 2013-01-01

Deuterium Metabolic Imaging—Rediscovery of a Spectroscopic Tool

by Ilona Polvoy, Hecong Qin, Robert R. Flavell, Jeremy Gordon, Pavithra Viswanath, Renuka Sriram, Michael A. Ohliger, David M. Wilson
Published 2021-08-01

Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1.

by Anton Simeonov, Avanti Kulkarni, Dorjbal Dorjsuren, Ajit Jadhav, Min Shen, Daniel R McNeill, Christopher P Austin, David M Wilson
Published 2009-06-01

Androgen receptor-binding sites are highly mutated in prostate cancer

by Tunç Morova, Daniel R. McNeill, Nada Lallous, Mehmet Gönen, Kush Dalal, David M. Wilson, Attila Gürsoy, Özlem Keskin, Nathan A. Lack
Published 2020-02-01

Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1-13C]gluconolactone

by Georgios Batsios, Céline Taglang, Peng Cao, Anne Marie Gillespie, Chloé Najac, Elavarasan Subramani, David M. Wilson, Robert R. Flavell, Peder E. Z. Larson, Sabrina M. Ronen, Pavithra Viswanath
Published 2021-04-01

Lucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein binding.

by Mamta D Naidu, Rakhi Agarwal, Louis A Pena, Luis Cunha, Mihaly Mezei, Min Shen, David M Wilson, Yuan Liu, Zina Sanchez, Pankaj Chaudhary, Samuel H Wilson, Michael J Waring
Published 2011-01-01

Imaging Active Infection in vivo Using D-Amino Acid Derived PET Radiotracers

by Kiel D. Neumann, Javier E. Villanueva-Meyer, Christopher A. Mutch, Robert R. Flavell, Joseph E. Blecha, Tiffany Kwak, Renuka Sriram, Henry F. VanBrocklin, Oren S. Rosenberg, Michael A. Ohliger, David M. Wilson
Published 2017-08-01

FEN1 Blockade for Platinum Chemo-Sensitization and Synthetic Lethality in Epithelial Ovarian Cancers

by Katia A. Mesquita, Reem Ali, Rachel Doherty, Michael S. Toss, Islam Miligy, Adel Alblihy, Dorjbal Dorjsuren, Anton Simeonov, Ajit Jadhav, David M. Wilson, Ian Hickson, Natalie J. Tatum, Emad A. Rakha, Srinivasan Madhusudan
Published 2021-04-01

A new in vivo screening paradigm to accelerate antimalarial drug discovery.

by María Belén Jiménez-Díaz, Sara Viera, Javier Ibáñez, Teresa Mulet, Noemí Magán-Marchal, Helen Garuti, Vanessa Gómez, Lorena Cortés-Gil, Antonio Martínez, Santiago Ferrer, María Teresa Fraile, Félix Calderón, Esther Fernández, Leonard D Shultz, Didier Leroy, David M Wilson, José Francisco García-Bustos, Francisco Javier Gamo, Iñigo Angulo-Barturen
Published 2013-01-01

A Therapeutic Uricase with Reduced Immunogenicity Risk and Improved Development Properties.

by Andrew C Nyborg, Chris Ward, Anna Zacco, Benoy Chacko, Luba Grinberg, James C Geoghegan, Ryan Bean, Michaela Wendeler, Frank Bartnik, Ellen O'Connor, Flaviu Gruia, Vidyashankara Iyer, Hui Feng, Varnika Roy, Mark Berge, Jeffrey N Miner, David M Wilson, Dongmei Zhou, Simone Nicholson, Clynn Wilker, Chi Y Wu, Susan Wilson, Lutz Jermutus, Herren Wu, David A Owen, Jane Osbourn, Steven Coats, Manuel Baca
Published 2016-01-01

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.

by Rahul S Desikan, Chun Chieh Fan, Yunpeng Wang, Andrew J Schork, Howard J Cabral, L Adrienne Cupples, Wesley K Thompson, Lilah Besser, Walter A Kukull, Dominic Holland, Chi-Hua Chen, James B Brewer, David S Karow, Karolina Kauppi, Aree Witoelar, Celeste M Karch, Luke W Bonham, Jennifer S Yokoyama, Howard J Rosen, Bruce L Miller, William P Dillon, David M Wilson, Christopher P Hess, Margaret Pericak-Vance, Jonathan L Haines, Lindsay A Farrer, Richard Mayeux, John Hardy, Alison M Goate, Bradley T Hyman, Gerard D Schellenberg, Linda K McEvoy, Ole A Andreassen, Anders M Dale
Published 2017-03-01

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia

by Adriana E. Tron, Matthew A. Belmonte, Ammar Adam, Brian M. Aquila, Lawrence H. Boise, Elisabetta Chiarparin, Justin Cidado, Kevin J. Embrey, Eric Gangl, Francis D. Gibbons, Gareth P. Gregory, David Hargreaves, J. Adam Hendricks, Jeffrey W. Johannes, Ricky W. Johnstone, Steven L. Kazmirski, Jason G. Kettle, Michelle L. Lamb, Shannon M. Matulis, Ajay K. Nooka, Martin J. Packer, Bo Peng, Philip B. Rawlins, Daniel W. Robbins, Alwin G. Schuller, Nancy Su, Wenzhan Yang, Qing Ye, Xiaolan Zheng, J. Paul Secrist, Edwin A. Clark, David M. Wilson, Stephen E. Fawell, Alexander W. Hird
Published 2018-12-01