Engineered Mammalian RNAi Can Elicit Antiviral Protection that Negates the Requirement for the Interferon Response

by Asiel Arturo Benitez, Laura Adrienne Spanko, Mehdi Bouhaddou, David Sachs, Benjamin Robert tenOever
Published 2015-11-01

Mutational Analysis of Measles Virus Suggests Constraints on Antigenic Variation of the Glycoproteins

by Benjamin O. Fulton, David Sachs, Shannon M. Beaty, Sohui T. Won, Benhur Lee, Peter Palese, Nicholas S. Heaton
Published 2015-06-01

A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host Factor

by Brook E. Heaton, Edward M. Kennedy, Rebekah E. Dumm, Alfred T. Harding, Matthew T. Sacco, David Sachs, Nicholas S. Heaton
Published 2017-08-01

The Mammalian Response to Virus Infection Is Independent of Small RNA Silencing

by Simone Backes, Ryan A. Langlois, Sonja Schmid, Andrew Varble, Jaehee V. Shim, David Sachs, Benjamin R. tenOever
Published 2014-07-01

Genome-wide transposon mutagenesis of paramyxoviruses reveals constraints on genomic plasticity.

by Satoshi Ikegame, Shannon M Beaty, Christian Stevens, Taylor Won, Arnold Park, David Sachs, Patrick Hong, Benhur Lee, Patricia A Thibault
Published 2020-10-01

In Vivo RNAi Screening Identifies MDA5 as a Significant Contributor to the Cellular Defense against Influenza A Virus

by Asiel A. Benitez, Maryline Panis, Jia Xue, Andrew Varble, Jaehee V. Shim, Amy L. Frick, Carolina B. López, David Sachs, Benjamin R. tenOever
Published 2015-06-01

Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses

by Raquel Muñoz-Moreno, Carles Martínez-Romero, Daniel Blanco-Melo, Christian V. Forst, Raffael Nachbagauer, Asiel Arturo Benitez, Ignacio Mena, Sadaf Aslam, Vinod Balasubramaniam, Ilseob Lee, Maryline Panis, Juan Ayllón, David Sachs, Man-Seong Park, Florian Krammer, Benjamin R. tenOever, Adolfo García-Sastre
Published 2019-12-01