Prorocentrolide-A from Cultured Prorocentrum lima Dinoflagellates Collected in Japan Blocks Sub-Types of Nicotinic Acetylcholine Receptors

by Muriel Amar, Rómulo Aráoz, Bogdan I. Iorga, Takeshi Yasumoto, Denis Servent, Jordi Molgó
Published 2018-02-01

Corrigendum: The NaV1.7 Channel Subtype as an Antinociceptive Target for Spider Toxins in Adult Dorsal Root Ganglia Neurons

by Tânia C. Gonçalves, Tânia C. Gonçalves, Evelyne Benoit, Evelyne Benoit, Michel Partiseti, Denis Servent
Published 2018-10-01

The NaV1.7 Channel Subtype as an Antinociceptive Target for Spider Toxins in Adult Dorsal Root Ganglia Neurons

by Tânia C. Gonçalves, Tânia C. Gonçalves, Evelyne Benoit, Evelyne Benoit, Michel Partiseti, Denis Servent
Published 2018-09-01

The Dinoflagellate Toxin 20-Methyl Spirolide-G Potently Blocks Skeletal Muscle and Neuronal Nicotinic Acetylcholine Receptors

by Aurélie Couesnon, Rómulo Aráoz, Bogdan I. Iorga, Evelyne Benoit, Morgane Reynaud, Denis Servent, Jordi Molgó
Published 2016-08-01

Synthetic Pinnatoxins A and G Reversibly Block Mouse Skeletal Neuromuscular Transmission In Vivo and In Vitro

by Evelyne Benoit, Aurélie Couesnon, Jiri Lindovsky, Bogdan I. Iorga, Rómulo Aráoz, Denis Servent, Armen Zakarian, Jordi Molgó
Published 2019-05-01

Alterations of peripheral nerve excitability in an experimental autoimmune encephalomyelitis mouse model for multiple sclerosis

by Nathalia Bernardes Teixeira, Gisele Picolo, Aline Carolina Giardini, Fawzi Boumezbeur, Géraldine Pottier, Bertrand Kuhnast, Denis Servent, Evelyne Benoit
Published 2020-09-01

Characterization of a Novel Conus bandanus Conopeptide Belonging to the M-Superfamily Containing Bromotryptophan

by Bao Nguyen, Jean-Pierre Le Caer, Gilles Mourier, Robert Thai, Hung Lamthanh, Denis Servent, Evelyne Benoit, Jordi Molgó
Published 2014-06-01

Ancestral protein resurrection and engineering opportunities of the mamba aminergic toxins

by Guillaume Blanchet, Doria Alili, Adèle Protte, Gregory Upert, Nicolas Gilles, Livia Tepshi, Enrico A. Stura, Gilles Mourier, Denis Servent
Published 2017-06-01

Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors.

by Carole Fruchart-Gaillard, Gilles Mourier, Guillaume Blanchet, Laura Vera, Nicolas Gilles, Renée Ménez, Elodie Marcon, Enrico A Stura, Denis Servent
Published 2012-01-01

Neonicotinoid binding, toxicity and expression of nicotinic acetylcholine receptor subunits in the aphid Acyrthosiphon pisum.

by Emiliane Taillebois, Abdelhamid Beloula, Sophie Quinchard, Stéphanie Jaubert-Possamai, Antoine Daguin, Denis Servent, Denis Tagu, Steeve H Thany, Hélène Tricoire-Leignel
Published 2014-01-01

Evaluation of the Spider (<i>Phlogiellus</i> genus) Phlotoxin 1 and Synthetic Variants as Antinociceptive Drug Candidates

by Tânia C. Gonçalves, Pierre Lesport, Sarah Kuylle, Enrico Stura, Justyna Ciolek, Gilles Mourier, Denis Servent, Emmanuel Bourinet, Evelyne Benoit, Nicolas Gilles
Published 2019-08-01

The Repellent DEET Potentiates Carbamate Effects via Insect Muscarinic Receptor Interactions: An Alternative Strategy to Control Insect Vector-Borne Diseases.

by Aly Abd-Ella, Maria Stankiewicz, Karolina Mikulska, Wieslaw Nowak, Cédric Pennetier, Mathilde Goulu, Carole Fruchart-Gaillard, Patricia Licznar, Véronique Apaire-Marchais, Olivier List, Vincent Corbel, Denis Servent, Bruno Lapied
Published 2015-01-01

Aptamer Efficacies for In Vitro and In Vivo Modulation of αC-Conotoxin PrXA Pharmacology

by Germain Sotoing Taiwe, Jérôme Montnach, Sébastien Nicolas, Stéphan De Waard, Emmanuelle Fiore, Eric Peyrin, Tarek Mohamed Abd El-Aziz, Muriel Amar, Jordi Molgó, Michel Ronjat, Denis Servent, Corinne Ravelet, Michel De Waard
Published 2019-01-01

RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia

by Sean B. Christensen, Arik J. Hone, Isabelle Roux, Julie Kniazeff, Jean-Philippe Pin, Grégory Upert, Denis Servent, Elisabeth Glowatzki, Elisabeth Glowatzki, J. Michael McIntosh, J. Michael McIntosh, J. Michael McIntosh
Published 2017-07-01

Efficient functional neutralization of lethal peptide toxins in vivo by oligonucleotides

by Tarek Mohamed Abd El-Aziz, Corinne Ravelet, Jordi Molgo, Emmanuelle Fiore, Simon Pale, Muriel Amar, Sawsan Al-Khoury, Jérôme Dejeu, Mahmoud Fadl, Michel Ronjat, Germain Sotoing Taiwe, Denis Servent, Eric Peyrin, Michel De Waard
Published 2017-08-01

Orthosteric binding of ρ-Da1a, a natural peptide of snake venom interacting selectively with the α1A-adrenoceptor.

by Arhamatoulaye Maïga, Jon Merlin, Elodie Marcon, Céline Rouget, Maud Larregola, Bernard Gilquin, Carole Fruchart-Gaillard, Evelyne Lajeunesse, Charles Marchetti, Alain Lorphelin, Laurent Bellanger, Roger J Summers, Dana S Hutchinson, Bronwyn A Evans, Denis Servent, Nicolas Gilles
Published 2013-01-01