Mitochondrial Calcium Increase Induced by RyR1 and IP3R Channel Activation After Membrane Depolarization Regulates Skeletal Muscle Metabolism

by Alexis R. Díaz-Vegas, Alex Cordova, Denisse Valladares, Denisse Valladares, Paola Llanos, Paola Llanos, Cecilia Hidalgo, Gaia Gherardi, Diego De Stefani, Cristina Mammucari, Rosario Rizzuto, Ariel Contreras-Ferrat, Enrique Jaimovich
Published 2018-06-01

Electrical stimuli are anti-apoptotic in skeletal muscle via extracellular ATP. Alteration of this signal in Mdx mice is a likely cause of dystrophy.

by Denisse Valladares, Gonzalo Almarza, Ariel Contreras, Mario Pavez, Sonja Buvinic, Enrique Jaimovich, Mariana Casas
Published 2013-01-01

Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and improves muscle function in dystrophic mdx mice.

by Francisco Altamirano, Denisse Valladares, Carlos Henríquez-Olguín, Mariana Casas, Jose R López, Paul D Allen, Enrique Jaimovich
Published 2013-01-01

NLRP3 Inflammasome: Potential Role in Obesity Related Low-Grade Inflammation and Insulin Resistance in Skeletal Muscle

by Gonzalo Jorquera, Javier Russell, Matías Monsalves-Álvarez, Gonzalo Cruz, Denisse Valladares-Ide, Carla Basualto-Alarcón, Genaro Barrientos, Manuel Estrada, Paola Llanos
Published 2021-03-01

GSK-3β/NFAT Signaling Is Involved in Testosterone-Induced Cardiac Myocyte Hypertrophy.

by Javier Duran, Cesar Oyarce, Mario Pavez, Denisse Valladares, Carla Basualto-Alarcon, Daniel Lagos, Genaro Barrientos, Mayarling Francisca Troncoso, Cristian Ibarra, Manuel Estrada
Published 2016-01-01

Moderate Exercise in Spontaneously Hypertensive Rats Is Unable to Activate the Expression of Genes Linked to Mitochondrial Dynamics and Biogenesis in Cardiomyocytes

by Clara Quiroga, Clara Quiroga, Georthan Mancilla, Ingrid Oyarzun, Anita Tapia, Mia Caballero, Luigi A. Gabrielli, Luigi A. Gabrielli, Denisse Valladares-Ide, Andrea del Campo, Pablo F. Castro, Pablo F. Castro, Hugo E. Verdejo, Hugo E. Verdejo
Published 2020-08-01