Serological Assessment of Activated Fibroblasts by alpha-Smooth Muscle Actin (α-SMA): A Noninvasive Biomarker of Activated Fibroblasts in Lung Disorders

by Signe Holm Nielsen, Nicholas Willumsen, Diana Julie Leeming, Samuel Joseph Daniels, Susanne Brix, Morten Asser Karsdal, Federica Genovese, Mette Juul Nielsen
Published 2019-02-01

MMP mediated degradation of type IV collagen alpha 1 and alpha 3 chains reflects basement membrane remodeling in experimental and clinical fibrosis--validation of two novel biomark...

by Jannie Marie Sand, Lise Larsen, Cory Hogaboam, Fernando Martinez, Meilan Han, Martin Røssel Larsen, Arkadiusz Nawrocki, Qinlong Zheng, Morten Asser Karsdal, Diana Julie Leeming
Published 2013-01-01

Determining a healthy reference range and factors potentially influencing PRO-C3 – A biomarker of liver fibrosis

by Elisabeth Erhardtsen, Daniel G.K. Rasmussen, Peder Frederiksen, Diana Julie Leeming, Diane Shevell, Lise Lotte Gluud, Morten Asser Karsdal, Guruprasad P. Aithal, Jörn M. Schattenberg
Published 2021-08-01

No effect of rifaximin on soluble CD163, mannose receptor or type III and IV neoepitope collagen markers in decompensated cirrhosis: Results from a randomized, placebo controlled t...

by Nina Kimer, Natasja Stæhr Gudmann, Julie Steen Pedersen, Søren Møller, Mette Juul Nielsen, Diana Julie Leeming, Morten Asser Karsdal, Holger Jon Møller, Flemming Bendtsen, Henning Grønbæk
Published 2018-01-01

Type IV collagen turnover is predictive of mortality in COPD: a comparison to fibrinogen in a prospective analysis of the ECLIPSE cohort

by Sarah Rank Rønnow, Jannie Marie Bülow Sand, Lasse Løcke Langholm, Tina Manon-Jensen, Morten Asser Karsdal, Ruth Tal-Singer, Bruce E. Miller, Jørgen Vestbo, Diana Julie Leeming
Published 2019-04-01

MMP mediated degradation of type VI collagen is highly associated with liver fibrosis--identification and validation of a novel biochemical marker assay.

by Sanne Skovgård Veidal, Morten Asser Karsdal, Efstathios Vassiliadis, Arkadiusz Nawrocki, Martin Røssel Larsen, Quoc Hai Trieu Nguyen, Per Hägglund, Yunyun Luo, Qinlong Zheng, Ben Vainer, Diana Julie Leeming
Published 2011-01-01

Measurement of CO3-610, a Potential Liver Biomarker Derived from Matrix Metalloproteinase-9 Degradation of Collagen Type III, in a Rat Model of Reversible Carbon-Tetrachloride-Indu...

by Efstathios Vassiliadis, Dorthe Vang Larsen, Rikke Elgaard Clausen, Sanne Skovgård Veidal, Natasha Barascuk, Lise Larsen, Henrik Simonsen, Toni Segovia Silvestre, Christina Hansen, Trine Overgaard, Diana Julie Leeming, Morten A Karsdal
Published 2011-01-01

Measurement of CO3-610, a Potential Liver Biomarker Derived from Matrix Metalloproteinase-9 Degradation of Collagen Type III, in a Rat Model of Reversible Carbon-Tetrachloride-Indu...

by Efstathios Vassiliadis, Dorthe Vang Larsen, Rikke Elgaard Clausen, Sanne Skovgård Veidal, Natasha Barascuk, Lise Larsen, Henrik Simonsen, Toni Segovia Silvestre, Christina Hansen, Trine Overgaard, Diana Julie Leeming, Morten A Karsdal
Published 2011-03-01

Serum markers of the extracellular matrix remodelling reflect antifibrotic therapy in bile-duct ligated rats.

by Robert eSchierwagen, Sabine eKlein, Diana Julie Leeming, Michaela eGranzow, Mette Juul Nielsen, Tilman eSauerbruch, Aleksander eKrag, Morten A Karlsdal, Morten A Karlsdal, Jonel eTrebicka
Published 2013-07-01

Comprehensive assessment of ECM turnover using serum biomarkers establishes PBC as a high-turnover autoimmune liver disease

by Mette Vesterhus, Mette Juul Nielsen, Johannes Roksund Hov, Francesca Saffioti, Tina Manon-Jensen, Diana Julie Leeming, Bjørn Moum, Kirsten Muri Boberg, Massimo Pinzani, Tom Hemming Karlsen, Morten Asser Karsdal, Douglas Thorburn
Published 2021-02-01

Prolonged Scar-in-a-Jar: an in vitro screening tool for anti-fibrotic therapies using biomarkers of extracellular matrix synthesis

by Sarah Rank Rønnow, Rand Qais Dabbagh, Federica Genovese, Carmel B. Nanthakumar, Vikki J. Barrett, Robert B. Good, Sarah Brockbank, Simon Cruwys, Henrik Jessen, Grith Lykke Sorensen, Morten Asser Karsdal, Diana Julie Leeming, Jannie Marie Bülow Sand
Published 2020-05-01