Senescence explains age- and obesity-related liver steatosis

by Mikolaj Ogrodnik, Diana Jurk
Published 2017-09-01

A stochastic step model of replicative senescence explains ROS production rate in ageing cell populations.

by Conor Lawless, Diana Jurk, Colin S Gillespie, Daryl Shanley, Gabriele Saretzki, Thomas von Zglinicki, João F Passos
Published 2012-01-01

Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk

by Liam D. Cassidy, Andrew R. J. Young, Christopher N. J. Young, Elizabeth J. Soilleux, Edward Fielder, Bettina M. Weigand, Anthony Lagnado, Rebecca Brais, Nicholas T. Ktistakis, Kimberley A. Wiggins, Katerina Pyrillou, Murray C. H. Clarke, Diana Jurk, Joao F. Passos, Masashi Narita
Published 2020-01-01

Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis

by Bernadette Carroll, Elsje G. Otten, Diego Manni, Rhoda Stefanatos, Fiona M. Menzies, Graham R. Smith, Diana Jurk, Niall Kenneth, Simon Wilkinson, Joao F. Passos, Johannes Attems, Elizabeth A. Veal, Elisa Teyssou, Danielle Seilhean, Stéphanie Millecamps, Eeva-Liisa Eskelinen, Agnieszka K. Bronowska, David C. Rubinsztein, Alberto Sanz, Viktor I. Korolchuk
Published 2018-01-01

Cellular senescence drives age-dependent hepatic steatosis

by Mikolaj Ogrodnik, Satomi Miwa, Tamar Tchkonia, Dina Tiniakos, Caroline L. Wilson, Albert Lahat, Christoper P. Day, Alastair Burt, Allyson Palmer, Quentin M. Anstee, Sushma Nagaraja Grellscheid, Jan H J. Hoeijmakers, Sander Barnhoorn, Derek A. Mann, Thomas G. Bird, Wilbert P. Vermeij, James L. Kirkland, João F. Passos, Thomas von Zglinicki, Diana Jurk
Published 2017-06-01