A comparison of RSV and influenza in vitro kinetic parameters reveals differences in infecting time.

by Gilberto Gonzàlez-Parra, Filip De Ridder, Dymphy Huntjens, Dirk Roymans, Gabriela Ispas, Hana M Dobrovolny
Published 2018-01-01

Development of a Stable Respiratory Syncytial Virus Pre-Fusion Protein Powder Suitable for a Core-Shell Implant with a Delayed Release in Mice: A Proof of Concept Study

by Max Beugeling, Katie Amssoms, Freek Cox, Ben De Clerck, Ellen Van Gulck, Jeroen A. Verwoerd, Guenter Kraus, Dirk Roymans, Lieven Baert, Henderik W. Frijlink, Wouter L. J. Hinrichs
Published 2019-10-01

The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2'-O-methylation.

by Priscila Sutto-Ortiz, Sergey Tcherniuk, Nina Ysebaert, Pravien Abeywickrema, Mathieu Noël, Alice Decombe, Françoise Debart, Jean-Jacques Vasseur, Bruno Canard, Dirk Roymans, Peter Rigaux, Jean-François Eléouët, Etienne Decroly
Published 2021-05-01

Antiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate Model.

by Gabriela Ispas, Anil Koul, Johan Verbeeck, Jennifer Sheehan, Brigitte Sanders-Beer, Dirk Roymans, Koen Andries, Marie-Claude Rouan, Sandra De Jonghe, Jean-François Bonfanti, Marc Vanstockem, Kenneth Simmen, Rene Verloes
Published 2015-01-01

Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.

by Harrison G Jones, Tina Ritschel, Gabriel Pascual, Just P J Brakenhoff, Elissa Keogh, Polina Furmanova-Hollenstein, Ellen Lanckacker, Jehangir S Wadia, Morgan S A Gilman, R Anthony Williamson, Dirk Roymans, Angélique B van 't Wout, Johannes P Langedijk, Jason S McLellan
Published 2018-03-01

Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor

by Dirk Roymans, Sarhad S Alnajjar, Michael B Battles, Panchan Sitthicharoenchai, Polina Furmanova-Hollenstein, Peter Rigaux, Joke Van den Berg, Leen Kwanten, Marcia Van Ginderen, Nick Verheyen, Luc Vranckx, Steffen Jaensch, Eric Arnoult, Richard Voorzaat, Jack M. Gallup, Alejandro Larios-Mora, Marjolein Crabbe, Dymphy Huntjens, Pierre Raboisson, Johannes P. Langedijk, Mark R. Ackermann, Jason S McLellan, Sandrine Vendeville, Anil Koul
Published 2017-08-01