Challenges with Approved Targeted Therapies against Recurrent Mutations in CLL: A Place for New Actionable Targets

by Irene López-Oreja, Heribert Playa-Albinyana, Fabián Arenas, Mónica López-Guerra, Dolors Colomer
Published 2021-06-01

Cyclin D1-CDK4 activity drives sensitivity to bortezomib in mantle cell lymphoma by blocking autophagy-mediated proteolysis of NOXA

by Simon Heine, Markus Kleih, Neus Giménez, Kathrin Böpple, German Ott, Dolors Colomer, Walter E. Aulitzky, Heiko van der Kuip, Elisabeth Silkenstedt
Published 2018-09-01

Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia

by Neus Gimenez, Rupal Tripathi, Ariadna Giró, Laia Rosich, Mònica López-Guerra, Irene López-Oreja, Heribert Playa-Albinyana, Fabian Arenas, José Manuel Mas, Patricia Pérez-Galán, Julio Delgado, Elias Campo, Judith Farrés, Dolors Colomer
Published 2020-12-01

Sampling time-dependent artifacts in single-cell genomics studies

by Ramon Massoni-Badosa, Giovanni Iacono, Catia Moutinho, Marta Kulis, Núria Palau, Domenica Marchese, Javier Rodríguez-Ubreva, Esteban Ballestar, Gustavo Rodriguez-Esteban, Sara Marsal, Marta Aymerich, Dolors Colomer, Elias Campo, Antonio Julià, José Ignacio Martín-Subero, Holger Heyn
Published 2020-05-01

Notch1 signaling in NOTCH1-mutated mantle cell lymphoma depends on Delta-Like ligand 4 and is a potential target for specific antibody therapy

by Elisabeth Silkenstedt, Fabian Arenas, Berta Colom-Sanmartí, Sílvia Xargay-Torrent, Morihiro Higashi, Ariadna Giró, Vanina Rodriguez, Patricia Fuentes, Walter E. Aulitzky, Heiko van der Kuip, Sílvia Beà, Maria L. Toribio, Elias Campo, Mònica López-Guerra, Dolors Colomer
Published 2019-11-01

Clinicobiological Characteristics and Outcomes of Patients with T-Cell Large Granular Lymphocytic Leukemia and Chronic Lymphoproliferative Disorder of Natural Killer Cells from a S...

by Andrea Rivero, Pablo Mozas, Laura Jiménez, Mónica López-Guerra, Dolors Colomer, Alex Bataller, Juan Correa, Alfredo Rivas-Delgado, Gabriela Bastidas, Tycho Baumann, Alejandra Martínez-Trillos, Julio Delgado, Eva Giné, Elías Campo, Armando López-Guillermo, Neus Villamor, Laura Magnano, Estella Matutes
Published 2021-08-01

Defining an Ultra-Low Risk Group in Asymptomatic IgM Monoclonal Gammopathy

by David F. Moreno, Arturo Pereira, Natalia Tovar, María Teresa Cibeira, Laura Magnano, María Rozman, Mónica López-Guerra, Dolors Colomer, Beatriz Martín-Antonio, Raquel Jiménez-Segura, Ignacio Isola, Luis Gerardo Rodríguez-Lobato, Aina Oliver-Caldés, Mari Pau Mena, Laura Rosiñol, Joan Bladé, Carlos Fernández de Larrea
Published 2021-04-01

Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation

by Roser Vilarrasa-Blasi, Paula Soler-Vila, Núria Verdaguer-Dot, Núria Russiñol, Marco Di Stefano, Vicente Chapaprieta, Guillem Clot, Irene Farabella, Pol Cuscó, Marta Kulis, Xabier Agirre, Felipe Prosper, Renée Beekman, Silvia Beà, Dolors Colomer, Hendrik G. Stunnenberg, Ivo Gut, Elias Campo, Marc A. Marti-Renom, José Ignacio Martin-Subero
Published 2021-01-01

IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms

by Ferran Nadeu, Rut Mas-de-les-Valls, Alba Navarro, Romina Royo, Silvia Martín, Neus Villamor, Helena Suárez-Cisneros, Rosó Mares, Junyan Lu, Anna Enjuanes, Alfredo Rivas-Delgado, Marta Aymerich, Tycho Baumann, Dolors Colomer, Julio Delgado, Ryan D. Morin, Thorsten Zenz, Xose S. Puente, Peter J. Campbell, Sílvia Beà, Francesco Maura, Elías Campo
Published 2020-07-01