Targeting the Mutational Landscape of Bystander Cells: Drug-Promoted Blood Cancer From High-Prevalence Pre-neoplasias in Patients on BRAF Inhibitors

by Donjete Simnica, Donjete Simnica, Harald Ittrich, Carsten Bockemeyer, Alexander Stein, Alexander Stein, Mascha Binder, Mascha Binder
Published 2020-09-01

T cell receptor next-generation sequencing reveals cancer-associated repertoire metrics and reconstitution after chemotherapy in patients with hematological and solid tumors

by Donjete Simnica, Nuray Akyüz, Simon Schliffke, Malte Mohme, Lisa v.Wenserski, Thorben Mährle, Lorenzo F. Fanchi, Katrin Lamszus, Mascha Binder
Published 2019-11-01

High-Throughput Immunogenetics Reveals a Lack of Physiological T Cell Clusters in Patients With Autoimmune Cytopenias

by Donjete Simnica, Simon Schliffke, Christoph Schultheiß, Nicola Bonzanni, Lorenzo F. Fanchi, Nuray Akyüz, Barbara Gösch, Christian Casar, Christian Casar, Benjamin Thiele, Janina Schlüter, Ansgar W. Lohse, Mascha Binder
Published 2019-08-01

Inflammasome Signaling Regulates the Microbial–Neuroimmune Axis and Visceral Pain in Mice

by Mònica Aguilera, Valerio Rossini, Ana Hickey, Donjete Simnica, Fiona Grady, Valeria D. Felice, Amy Moloney, Lauren Pawley, Aine Fanning, Lorraine McCarthy, Siobhan M. O’Mahony, John F. Cryan, Ken Nally, Fergus Shanahan, Silvia Melgar
Published 2021-08-01

Landscape of T‐cell repertoires with public COVID‐19‐associated T‐cell receptors in pre‐pandemic risk cohorts

by Donjete Simnica, Christoph Schultheiß, Malte Mohme, Lisa Paschold, Edith Willscher, Antonia Fitzek, Klaus Püschel, Jakob Matschke, Sandra Ciesek, Daniel G Sedding, Yu Zhao, Nicola Gagliani, Yacine Maringer, Juliane S Walz, Janna Heide, Julian Schulze‐zur‐Wiesch, Mascha Binder
Published 2021-01-01

PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer

by Thomas J Ettrich, Barbara Seliger, Chiara Massa, Alexander Stein, Claudia Wickenhauser, Axel Hinke, Uwe Pelzer, Carsten Bokemeyer, Marcus Bauer, Susanna Hegewisch-Becker, Donjete Simnica, Christoph Schultheiß, Rebekka Scholz, Joseph Tintelnot, Eray Gökkurt, Lisa von Wenserski, Edith Willscher, Lisa Paschold, Markus Sauer, Sylvie Lorenzen, Jorge Riera-Knorrenschild, Reinhard Depenbusch, Steffen Dörfel, Salah-Eddin Al-Batran, Meinolf Karthaus, Lisa Waberer, Mascha Binder
Published 2021-07-01