Developing an animal model to detect drug–drug interactions impacting drug-induced respiratory depression

by Lin Xu, Ashok Chockalingam, Sharron Stewart, Katherine Shea, Murali K. Matta, Suresh Narayanasamy, Nageswara R. Pilli, Donna A. Volpe, James Weaver, Hao Zhu, Michael C. Davis, David G. Strauss, Rodney Rouse
Published 2020-01-01

Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block.

by Phu N Tran, Jiansong Sheng, Aaron L Randolph, Claudia Alvarez Baron, Nicolas Thiebaud, Ming Ren, Min Wu, Lars Johannesen, Donna A Volpe, Dakshesh Patel, Ksenia Blinova, David G Strauss, Wendy W Wu
Published 2020-01-01

Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation

by Andrés Rubiano, Amruta Indapurkar, Ryosuke Yokosawa, Alina Miedzik, Barry Rosenzweig, Ayesha Arefin, Chloe M. Moulin, Keri Dame, Neil Hartman, Donna A. Volpe, Murali K. Matta, David J. Hughes, David G. Strauss, Tomasz Kostrzewski, Alexandre J. S. Ribeiro
Published 2021-05-01