Post-translational thioamidation of methyl-coenzyme M reductase, a key enzyme in methanogenic and methanotrophic Archaea

by Dipti D Nayak, Nilkamal Mahanta, Douglas A Mitchell, William W Metcalf
Published 2017-09-01

Crystal structure and absolute configuration of (3S,4aS,8aS)-N-tert-butyl-2-[(S)-3-(2-chloro-4-nitrobenzamido)-2-hydroxypropyl]decahydroisoquinoline-3-carboxamide and (3S,4aS,8aS)-...

by Tucker Maxson, Jeffery A. Bertke, Danielle L. Gray, Douglas A. Mitchell
Published 2015-11-01

Chimeric Leader Peptides for the Generation of Non-Natural Hybrid RiPP Products

by Brandon J. Burkhart, Nidhi Kakkar, Graham A. Hudson, Wilfred A. van der Donk, Douglas A. Mitchell
Published 2017-06-01

Precursor peptide-targeted mining of more than one hundred thousand genomes expands the lanthipeptide natural product family

by Mark C. Walker, Sara M. Eslami, Kenton J. Hetrick, Sarah E. Ackenhusen, Douglas A. Mitchell, Wilfred A. van der Donk
Published 2020-06-01

Functional interactions between posttranslationally modified amino acids of methyl-coenzyme M reductase in Methanosarcina acetivorans.

by Dipti D Nayak, Andi Liu, Neha Agrawal, Roy Rodriguez-Carerro, Shi-Hui Dong, Douglas A Mitchell, Satish K Nair, William W Metcalf
Published 2020-02-01