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El-Deiry, W.S
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El-Deiry, W.S
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Small-Molecule NSC59984 Induces Mutant p53 Degradation through a ROS-ERK2-MDM2 Axis in Cancer Cells
by
El
-
Deiry
,
W
.S
,
Zhang, S.
,
Zhou, L.
Published 2022
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Related Subjects
1-(4-methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one
Humans
MDM2 protein, human
Neoplasms
Nitrofurans
Phosphorylation
Piperazines
Proto-Oncogene Proteins c-mdm2
Reactive Oxygen Species
Tumor Suppressor Protein p53
genetics
human
metabolism
mouse double minute 2 homolog
neoplasm
nitrofuran derivative
phosphorylation
piperazine derivative
protein p53
reactive oxygen metabolite
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