Qualitative Differences in Protection of PTP1B Activity by the Reductive Trx1 or TRP14 Enzyme Systems upon Oxidative Challenges with Polysulfides or H₂O₂ Toge...

by Markus Dagnell, Qing Cheng, Elias S.J. Arnér
Published 2021-01-01

To inhibit TrxR1 is to inactivate STAT3–Inhibition of TrxR1 enzymatic function by STAT3 small molecule inhibitors

by Sander Busker, Brent Page, Elias S.J. Arnér
Published 2020-09-01

Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells.

by Karin Anestål, Stefanie Prast-Nielsen, Narimantas Cenas, Elias S J Arnér
Published 2008-04-01

Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone

by Nan Shu, Qing Cheng, Elias S.J. Arnér, Michael J. Davies
Published 2020-01-01

Time- and cell-resolved dynamics of redox-sensitive Nrf2, HIF and NF-κB activities in 3D spheroids enriched for cancer stem cells

by Anna P. Kipp, Stefanie Deubel, Elias S.J. Arnér, Katarina Johansson
Published 2017-08-01

Biochemical discrimination between selenium and sulfur 2: mechanistic investigation of the selenium specificity of human selenocysteine lyase.

by Ann-Louise Johansson, Ruairi Collins, Elias S J Arnér, Peter Brzezinski, Martin Högbom
Published 2012-01-01

Molecular Basis for the Interactions of Human Thioredoxins with Their Respective Reductases

by Md Faruq Hossain, Yana Bodnar, Calvin Klein, Clara Ortegón Salas, Elias S. J. Arnér, Manuela Gellert, Christopher Horst Lillig
Published 2021-01-01

Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target.

by Angela N Kuntz, Elisabeth Davioud-Charvet, Ahmed A Sayed, Lindsay L Califf, Jean Dessolin, Elias S J Arnér, David L Williams
Published 2007-06-01

Correction: Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target.

by Angela N Kuntz, Elisabeth Davioud-Charvet, Ahmed A Sayed, Lindsay L Califf, Jean Dessolin, Elias S. J Arnér, David L Williams
Published 2007-08-01

Identification and targeting of selective vulnerability rendered by tamoxifen resistance

by Madhurendra Singh, Xiaolei Zhou, Xinsong Chen, Gema Sanz Santos, Sylvain Peuget, Qing Cheng, Ali Rihani, Elias S. J. Arnér, Johan Hartman, Galina Selivanova
Published 2020-07-01

Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin

by Amir Ata Saei, Hjalmar Gullberg, Pierre Sabatier, Christian M. Beusch, Katarina Johansson, Bo Lundgren, Per I. Arvidsson, Elias S.J. Arnér, Roman A. Zubarev
Published 2020-05-01

Production and purification of homogenous recombinant human selenoproteins reveals a unique codon skipping event in E. coli and GPX4-specific affinity to bromosulfophthalein

by Qing Cheng, Antonella Roveri, Giorgio Cozza, Luciana Bordin, Isabelle Rohn, Tanja Schwerdtle, Anna Kipp, Fulvio Ursini, Matilde Maiorino, Giovanni Miotto, Elias S.J. Arnér
Published 2021-10-01

Biochemical discrimination between selenium and sulfur 1: a single residue provides selenium specificity to human selenocysteine lyase.

by Ruairi Collins, Ann-Louise Johansson, Tobias Karlberg, Natalia Markova, Susanne van den Berg, Kenneth Olesen, Martin Hammarström, Alex Flores, Herwig Schüler, Lovisa Holmberg Schiavone, Peter Brzezinski, Elias S J Arnér, Martin Högbom
Published 2012-01-01

Combining [11C]-AnxA5 PET imaging with serum biomarkers for improved detection in live mice of modest cell death in human solid tumor xenografts.

by Qing Cheng, Li Lu, Jonas Grafström, Maria Hägg Olofsson, Jan-Olov Thorell, Erik Samén, Katarina Johansson, Hanna-Stina Ahlzén, Sharon Stone-Elander, Stig Linder, Elias S J Arnér, Sel-tag Imaging Project
Published 2012-01-01

System-wide identification and prioritization of enzyme substrates by thermal analysis

by Amir Ata Saei, Christian M. Beusch, Pierre Sabatier, Juan Astorga Wells, Hassan Gharibi, Zhaowei Meng, Alexey Chernobrovkin, Sergey Rodin, Katja Näreoja, Ann-Gerd Thorsell, Tobias Karlberg, Qing Cheng, Susanna L. Lundström, Massimiliano Gaetani, Ákos Végvári, Elias S. J. Arnér, Herwig Schüler, Roman A. Zubarev
Published 2021-02-01

Hepatocyte Hyperproliferation upon Liver-Specific Co-disruption of Thioredoxin-1, Thioredoxin Reductase-1, and Glutathione Reductase

by Justin R. Prigge, Lucia Coppo, Sebastin S. Martin, Fernando Ogata, Colin G. Miller, Michael D. Bruschwein, David J. Orlicky, Colin T. Shearn, Jean A. Kundert, Julia Lytchier, Alix E. Herr, Åse Mattsson, Matthew P. Taylor, Tomas N. Gustafsson, Elias S.J. Arnér, Arne Holmgren, Edward E. Schmidt
Published 2017-06-01