Multiple roles and therapeutic implications of Akt signaling in cancer

by Emiliano Calvo, Victoria Bolós, Enrique Grande
Published 2009-06-01

412 First-in-human phase I/IIa trial to evaluate the safety and initial clinical activity of DuoBody®-PD-L1×4–1BB (GEN1046) in patients with advanced solid tumors

by Ignacio Melero, Emiliano Calvo, Patricia LoRusso, Ravit Geva, Elena Garralda, Eytan Ben-Ami, Corinne Maurice-Dror, Michelle Niewood, Ulf Forssmann
Published 2020-11-01

394 Interleukin-8–neutralizing monoclonal antibody BMS-986253 plus nivolumab (NIVO) in biomarker-enriched, primarily anti–PD-(L)1–experienced patients with advanced cancer: initial...

by Ignacio Melero, Diwakar Davar, Emiliano Calvo, Donald Richards, Sarina Piha-Paul, Matthew Dallos, Martin Gutierrez, Matteo Simonelli, Jason Melear, Janaki Parameswaran, Vinit Kumar, Xiaochen Zhao, Santanu Dutta
Published 2020-11-01

Safety and efficacy of AMG 820, an anti-colony-stimulating factor 1 receptor antibody, in combination with pembrolizumab in adults with advanced solid tumors

by Albiruni RA Razak, James M Cleary, Michael Boyer, Emiliano Calvo Aller, William Edenfield, R Donald Harvey, Annemie Rutten, David P Ryan, Hansen Wong, Neelesh Soman, Marie-Anne Damiette Smit
Published 2020-07-01

A phase 1 dose escalation study of the oncolytic adenovirus enadenotucirev, administered intravenously to patients with epithelial solid tumors (EVOLVE)

by Jean-Pascal Machiels, Ramon Salazar, Sylvie Rottey, Ignacio Duran, Luc Dirix, Karen Geboes, Christine Wilkinson-Blanc, Gillian Pover, Simon Alvis, Brian Champion, Kerry Fisher, Hilary McElwaine-Johnn, John Beadle, Emiliano Calvo
Published 2019-01-01

Phase 1 study of intravenous administration of the chimeric adenovirus enadenotucirev in patients undergoing primary tumor resection

by Rocio Garcia-Carbonero, Ramon Salazar, Ignacio Duran, Ignacio Osman-Garcia, Luis Paz-Ares, Juan M. Bozada, Valentina Boni, Christine Blanc, Len Seymour, John Beadle, Simon Alvis, Brian Champion, Emiliano Calvo, Kerry Fisher
Published 2017-09-01

ESMO Clinical Research Observatory (ECRO): improving the efficiency of clinical research through rationalisation of bureaucracy

by Hendrik-Tobias Arkenau, Jean-Yves Douillard, Nicolas Penel, Teresa Amaral, Ahmad Awada, Emiliano Calvo, Viktor Gruenwald, Jose Luis Perez-Gracia, Ruth Vera, Martijn P Lolkema, Gyorgy Bodoky, Massimo Di Nicola, Miguel F Sanmamed
Published 2020-05-01

Safety and activity of the TGFβ receptor I kinase inhibitor galunisertib plus the anti-PD-L1 antibody durvalumab in metastatic pancreatic cancer

by Antoine Hollebecque, Rocio Garcia-Carbonero, Do-Youn Oh, Emiliano Calvo, Davide Melisi, Teresa Macarulla, Valeria Merz, Erkut Borazanci, Anna Varghese, Camilla Zecchetto, Yumin Zhao, Ivelina Gueorguieva, Michael Man, Shawn T Estrem, Karim A Benhadji, Emin Avsar, Susan C Guba
Published 2021-03-01

Ramucirumab in Combination with Pembrolizumab in Treatment-Naïve Advanced Gastric or GEJ Adenocarcinoma: Safety and Antitumor Activity from the Phase 1a/b JVDF Trial

by Ian Chau, Nicolas Penel, Andres O. Soriano, Hendrik-Tobias Arkenau, Jennifer Cultrera, Rafael Santana-Davila, Emiliano Calvo, Christophe Le Tourneau, Lars Zender, Johanna C. Bendell, Gu Mi, Ling Gao, Samuel Clark McNeely, Joana M. Oliveira, David Ferry, Roy S. Herbst, Charles S. Fuchs
Published 2020-10-01