TREM2/PLCγ2 signalling in immune cells: function, structural insight, and potential therapeutic modulation

by Lorenza Magno, Tom D. Bunney, Emma Mead, Fredrik Svensson, Magda N. Bictash
Published 2021-04-01

PLCγ2 regulates TREM2 signalling and integrin-mediated adhesion and migration of human iPSC-derived macrophages

by Juliane Obst, Hazel L. Hall-Roberts, Thomas B. Smith, Mira Kreuzer, Lorenza Magno, Elena Di Daniel, John B. Davis, Emma Mead
Published 2021-10-01

TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages

by Hazel Hall-Roberts, Devika Agarwal, Juliane Obst, Thomas B. Smith, Jimena Monzón-Sandoval, Elena Di Daniel, Caleb Webber, William S. James, Emma Mead, John B. Davis, Sally A. Cowley
Published 2020-11-01

Control of translation elongation in health and disease

by John R. P. Knight, Gavin Garland, Tuija Pöyry, Emma Mead, Nikola Vlahov, Aristeidis Sfakianos, Stefano Grosso, Fabio De-Lima-Hedayioglu, Giovanna R. Mallucci, Tobias von der Haar, C. Mark Smales, Owen J. Sansom, Anne E. Willis
Published 2020-03-01