The histone demethylase LSD1 regulates inner ear progenitor differentiation through interactions with Pax2 and the NuRD repressor complex.

by Dharmeshkumar Patel, Atsushi Shimomura, Sreeparna Majumdar, Matthew C Holley, Eri Hashino
Published 2018-01-01

Tlx3 promotes glutamatergic neuronal subtype specification through direct interactions with the chromatin modifier CBP.

by Atsushi Shimomura, Dharmeshkumar Patel, Sarah M Wilson, Karl R Koehler, Rajesh Khanna, Eri Hashino
Published 2015-01-01

Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells

by Xiao-Ping Liu, Karl R. Koehler, Andrew M. Mikosz, Eri Hashino, Jeffrey R. Holt
Published 2016-05-01

Modulation of Wnt Signaling Enhances Inner Ear Organoid Development in 3D Culture.

by Rachel E DeJonge, Xiao-Ping Liu, Christopher R Deig, Stefan Heller, Karl R Koehler, Eri Hashino
Published 2016-01-01

Class I(A) PI3Kinase regulatory subunit, p85α, mediates mast cell development through regulation of growth and survival related genes.

by Subha Krishnan, Raghuveer Singh Mali, Karl R Koehler, Sasidhar Vemula, Anindya Chatterjee, Joydeep Ghosh, Baskar Ramdas, Peilin Ma, Eri Hashino, Reuben Kapur
Published 2012-01-01

Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids

by Pei-Ciao Tang, Alpha L. Alex, Jing Nie, Jiyoon Lee, Adam A. Roth, Kevin T. Booth, Karl R. Koehler, Eri Hashino, Rick F. Nelson
Published 2019-07-01