Use of recombinant adenovirus vectored consensus IFN-α to avert severe arenavirus infection.

by Brian B Gowen, Jane Ennis, Andrew Russell, Eric J Sefing, Min-Hui Wong, Jeffrey Turner
Published 2011-01-01

Type I interferon underlies severe disease associated with Junín virus infection in mice

by Brady T Hickerson, Eric J Sefing, Kevin W Bailey, Arnaud J Van Wettere, Manuel L Penichet, Brian B Gowen
Published 2020-05-01

Single-Dose Intranasal Treatment with DEF201 (Adenovirus Vectored Consensus Interferon) Prevents Lethal Disease Due to Rift Valley Fever Virus Challenge

by Brian B. Gowen, Jane Ennis, Kevin W. Bailey, Zachary Vest, Dionna Scharton, Eric J. Sefing, Jeffrey D. Turner
Published 2014-03-01

MP-12 virus containing the Clone 13 deletion in the NSs gene prevents lethal disease when administered after Rift Valley fever virus infection in hamsters

by Brian B Gowen, Brian B Gowen, Brian B Gowen, Jonna B Westover, Jonna B Westover, Eric J Sefing, Eric J Sefing, Kevin W Bailey, Kevin W Bailey, Shoko eNishiyama, Luci eWandersee, Luci eWandersee, Dionna eScharton, Dionna eScharton, Kie-Hoon eJung, Kie-Hoon eJung, Tetsuro eIkegami, Tetsuro eIkegami, Tetsuro eIkegami
Published 2015-06-01

Development of a new tacaribe arenavirus infection model and its use to explore antiviral activity of a novel aristeromycin analog.

by Brian B Gowen, Min-Hui Wong, Deanna Larson, Wei Ye, Kie-Hoon Jung, Eric J Sefing, Ramona Skirpstunas, Donald F Smee, John D Morrey, Stewart W Schneller
Published 2010-09-01

Favipiravir (T-705) inhibits Junín virus infection and reduces mortality in a guinea pig model of Argentine hemorrhagic fever.

by Brian B Gowen, Terry L Juelich, Eric J Sefing, Trevor Brasel, Jennifer K Smith, Lihong Zhang, Bersabeh Tigabu, Terence E Hill, Tatyana Yun, Colette Pietzsch, Yousuke Furuta, Alexander N Freiberg
Published 2013-01-01