Neurodegenerative Disease–Associated Variants in TREM2 Destabilize the Apical Ligand-Binding Region of the Immunoglobulin Domain

by Hunter B. Dean, Hunter B. Dean, Hunter B. Dean, Hunter B. Dean, Hunter B. Dean, Erik D. Roberson, Erik D. Roberson, Erik D. Roberson, Yuhua Song
Published 2019-11-01

Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency

by Andrew E. Arrant, Alexandra M. Nicholson, Xiaolai Zhou, Rosa Rademakers, Erik D. Roberson
Published 2018-06-01

A peptide inhibitor of Tau-SH3 interactions ameliorates amyloid-β toxicity

by Travis Rush, Jonathan R. Roth, Samantha J. Thompson, Adam R. Aldaher, J. Nicholas Cochran, Erik D. Roberson
Published 2020-02-01

Noradrenergic dysfunction in Alzheimer’s disease

by Mary eGannon, Pulin eChe, Yunjia eChen, Kai eJiao, Erik D Roberson, Qin eWang
Published 2015-06-01

Reduction of microglial progranulin does not exacerbate pathology or behavioral deficits in neuronal progranulin-insufficient mice

by Andrew E. Arrant, Anthony J. Filiano, Aashka R. Patel, Madelyn Q. Hoffmann, Nicholas R. Boyle, Shreya N. Kashyap, Vincent C. Onyilo, Allen H. Young, Erik D. Roberson
Published 2019-04-01

Alzheimer’s disease risk gene BIN1 induces Tau-dependent network hyperexcitability

by Yuliya Voskobiynyk, Jonathan R Roth, J Nicholas Cochran, Travis Rush, Nancy VN Carullo, Jacob S Mesina, Mohammad Waqas, Rachael M Vollmer, Jeremy J Day, Lori L McMahon, Erik D Roberson
Published 2020-07-01

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

by Yuliya Voskobiynyk, Gopal Battu, Stephanie A Felker, J Nicholas Cochran, Megan P Newton, Laura J Lambert, Robert A Kesterson, Richard M Myers, Gregory M Cooper, Erik D Roberson, Gregory S Barsh
Published 2021-01-01

Usp14 deficiency increases tau phosphorylation without altering tau degradation or causing tau-dependent deficits.

by Youngnam N Jin, Ping-Chung Chen, Jennifer A Watson, Brandon J Walters, Scott E Phillips, Karen Green, Robert Schmidt, Julie A Wilson, Gail V Johnson, Erik D Roberson, Lynn E Dobrunz, Scott M Wilson
Published 2012-01-01

Challenges and Opportunities for Characterizing Cognitive Aging across Species

by Erik D Roberson, R. Anthony DeFazio, Carol A. Barnes, Gene E. Alexander, Jennifer L. Bizon, Dawn eBowers, Thomas C Foster, Elizabeth L. Glisky, Bonnie E. Levin, Lee eRyan, Clinton B. Wright, David S. Geldmacher
Published 2012-09-01

Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations

by Andrew E. Arrant, Jonathan R. Roth, Nicholas R. Boyle, Shreya N. Kashyap, Madelyn Q. Hoffmann, Charles F. Murchison, Eliana Marisa Ramos, Alissa L. Nana, Salvatore Spina, Lea T. Grinberg, Bruce L. Miller, William W. Seeley, Erik D. Roberson
Published 2019-12-01

Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in amyloid precursor protein transgenic mice

by Allison R. Fusilier, Jennifer A. Davis, Jodi R. Paul, Stefani D. Yates, Laura J. McMeekin, Lacy K. Goode, Mugdha V. Mokashi, Natalie Remiszewski, Thomas van Groen, Rita M. Cowell, Lori L. McMahon, Erik D. Roberson, Karen L. Gamble
Published 2021-10-01

Comparison of Pittsburgh compound B and florbetapir in cross‐sectional and longitudinal studies

by Yi Su, Shaney Flores, Guoqiao Wang, Russ C. Hornbeck, Benjamin Speidel, Nelly Joseph‐Mathurin, Andrei G. Vlassenko, Brian A. Gordon, Robert A. Koeppe, William E. Klunk, Clifford R. Jack Jr., Martin R. Farlow, Stephen Salloway, Barbara J. Snider, Sarah B. Berman, Erik D. Roberson, Jared Brosch, Ivonne Jimenez‐Velazques, Christopher H. vanDyck, Douglas Galasko, Shauna H. Yuan, Suman Jayadev, Lawrence S. Honig, Serge Gauthier, Ging‐Yuek R. Hsiung, Mario Masellis, William S. Brooks, Michael Fulham, Roger Clarnette, Colin L. Masters, David Wallon, Didier Hannequin, Bruno Dubois, Jeremie Pariente, Raquel Sanchez‐Valle, Catherine Mummery, John M. Ringman, Michel Bottlaender, Gregory Klein, Smiljana Milosavljevic‐Ristic, Eric McDade, Chengjie Xiong, John C. Morris, Randall J. Bateman, Tammie L.S. Benzinger
Published 2019-12-01

Nonlinear Z‐score modeling for improved detection of cognitive abnormality

by John Kornak, Julie Fields, Walter Kremers, Sara Farmer, Hilary W. Heuer, Leah Forsberg, Danielle Brushaber, Amy Rindels, Hiroko Dodge, Sandra Weintraub, Lilah Besser, Brian Appleby, Yvette Bordelon, Jessica Bove, Patrick Brannelly, Christina Caso, Giovanni Coppola, Reilly Dever, Christina Dheel, Bradford Dickerson, Susan Dickinson, Sophia Dominguez, Kimiko Domoto‐Reilly, Kelley Faber, Jessica Ferrall, Ann Fishman, Jamie Fong, Tatiana Foroud, Ralitza Gavrilova, Deb Gearhart, Behnaz Ghazanfari, Nupur Ghoshal, Jill Goldman, Jonathan Graff‐Radford, Neill Graff‐Radford, Ian M. Grant, Murray Grossman, Dana Haley, John Hsiao, Robin Hsiung, Edward D. Huey, David Irwin, David Jones, Lynne Jones, Kejal Kantarci, Anna Karydas, Daniel Kaufer, Diana Kerwin, David Knopman, Ruth Kraft, Joel Kramer, Walter Kukull, Maria Lapid, Irene Litvan, Peter Ljubenkov, Diane Lucente, Codrin Lungu, Ian Mackenzie, Miranda Maldonado, Masood Manoochehri, Scott McGinnis, Emily McKinley, Mario Mendez, Bruce Miller, Namita Multani, Chiadi Onyike, Jaya Padmanabhan, Alexander Pantelyat, Rodney Pearlman, Len Petrucelli, Madeline Potter, Rosa Rademakers, Eliana Marisa Ramos, Katherine Rankin, Katya Rascovsky, Erik D. Roberson, Emily Rogalski‐Miller, Pheth Sengdy, Les Shaw, Adam M. Staffaroni, Margaret Sutherland, Jeremy Syrjanen, Carmela Tartaglia, Nadine Tatton, Joanne Taylor, Arthur Toga, John Trojanowski, Ping Wang, Bonnie Wong, Zbigniew Wszolek, Brad Boeve, Adam Boxer, Howard Rosen, ARTFL/LEFFTDS Consortium
Published 2019-12-01