Safety and long-term efficacy of AAV1.SERCA2a using nebulizer delivery in a pig model of pulmonary hypertension

by Shin Watanabe, Kiyotake Ishikawa, Maria Plataki, Olympia Bikou, Erik Kohlbrenner, Jaume Aguero, Lahouaria Hadri, Iratxe Zarragoikoetxea, Kenneth Fish, Jane A. Leopold, Roger J. Hajjar
Published 2018-09-01

Combination Therapy with STAT3 Inhibitor Enhances SERCA2a-Induced BMPR2 Expression and Inhibits Pulmonary Arterial Hypertension

by Malik Bisserier, Michael G. Katz, Carlos Bueno-Beti, Agnieszka Brojakowska, Shihong Zhang, Sarah Gubara, Erik Kohlbrenner, Shahood Fazal, Anthony Fargnoli, Peter Dorfmuller, Marc Humbert, Akiko Hata, David A. Goukassian, Yassine Sassi, Lahouaria Hadri
Published 2021-08-01

Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice

by Antanina Voit, Vishwendra Patel, Ronald Pachon, Vikas Shah, Mohammad Bakhutma, Erik Kohlbrenner, Joseph J. McArdle, Louis J. Dell’Italia, Jerry R. Mendell, Lai-Hua Xie, Roger J. Hajjar, Dongsheng Duan, Diego Fraidenraich, Gopal J. Babu
Published 2017-10-01