Targeting androgen receptor/Src complex impairs the aggressive phenotype of human fibrosarcoma cells.

by Gabriella Castoria, Pia Giovannelli, Marzia Di Donato, Ryo Hayashi, Claudio Arra, Ettore Appella, Ferdinando Auricchio, Antimo Migliaccio
Published 2013-01-01

Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation.

by Muhammad S Alam, Matthias M Gaida, Subrata Debnath, Harichandra D Tagad, Lisa M Miller Jenkins, Ettore Appella, M Jubayer Rahman, Jonathan D Ashwell
Published 2018-01-01

Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246

by Tomer Cooks, Ioannis S. Pateras, Lisa M. Jenkins, Keval M. Patel, Ana I. Robles, James Morris, Tim Forshew, Ettore Appella, Vassilis G. Gorgoulis, Curtis C. Harris
Published 2018-02-01

Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses

by Burhan Uyanik, Anastasia R. Goloudina, Aamir Akbarali, Bogdan B. Grigorash, Alexey V. Petukhov, Sunil Singhal, Evgeniy Eruslanov, Jeanne Chaloyard, Lisa Lagorgette, Tarik Hadi, Ekaterina V. Baidyuk, Hiroyasu Sakai, Lino Tessarollo, Bernhard Ryffel, Sharlyn J. Mazur, Frederic Lirussi, Carmen Garrido, Ettore Appella, Oleg N. Demidov
Published 2021-06-01