Role of Sex in the Therapeutic Targeting of p53 Circuitry

by Francesca Mancini, Ludovica Giorgini, Ludovica Giorgini, Emanuela Teveroni, Alfredo Pontecorvi, Fabiola Moretti
Published 2021-07-01

Effect of p53 activation through targeting MDM2/MDM4 heterodimer on T regulatory and effector cells in the peripheral blood of Type 1 diabetes patients.

by Marsha Pellegrino, Gianandrea Traversi, Andrea Arena, Marco Cappa, M Manuela Rosado, Marco Andreani, Domenico V Delfino, Fabiola Moretti, Alessandra Fierabracci
Published 2020-01-01

p53 Activation Effect in the Balance of T Regulatory and Effector Cell Subsets in Patients With Thyroid Cancer and Autoimmunity

by Andrea Arena, Antonio Stigliano, Eugenia Belcastro, Ezio Giorda, Maria Manuela Rosado, Maria Manuela Rosado, Armando Grossi, Maria Rita Assenza, Fabiola Moretti, Alessandra Fierabracci
Published 2021-08-01

Inhibition of the mTOR pathway and reprogramming of protein synthesis by MDM4 reduce ovarian cancer metastatic properties

by Rossella Lucà, Maria Rita Assenza, Fabio Maiullari, Luisa Pieroni, Silvia Maiullari, Giulia Federici, Federica Marini, Roberto Rizzi, Andrea Urbani, Silvia Soddu, Fabiola Moretti
Published 2021-05-01

Intake of Boron, Cadmium, and Molybdenum enhances rat thyroid cell transformation

by Emilia Luca, Laura Fici, Anna Ronchi, Ferdinando Marandino, Esther Diana Rossi, Maria Emiliana Caristo, Pasqualino Malandrino, Marco Russo, Alfredo Pontecorvi, Riccardo Vigneri, Fabiola Moretti
Published 2017-06-01

The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia

by Giusy Di Conza, Sarah Trusso Cafarello, Stefan Loroch, Daniela Mennerich, Sofie Deschoemaeker, Mario Di Matteo, Manuel Ehling, Kris Gevaert, Hans Prenen, Rene Peiman Zahedi, Albert Sickmann, Thomas Kietzmann, Fabiola Moretti, Massimiliano Mazzone
Published 2017-02-01

Estrogens Counteract Platinum-Chemosensitivity by Modifying the Subcellular Localization of MDM4

by Rossella Lucà, Giorgia di Blasio, Daniela Gallo, Valentina Monteleone, Isabella Manni, Laura Fici, Marianna Buttarelli, Germana Ciolli, Marsha Pellegrino, Emanuela Teveroni, Silvia Maiullari, Alessandra Ciucci, Alessandro Apollo, Francesca Mancini, Maria Pia Gentileschi, Gian Franco Zannoni, Alfredo Pontecorvi, Giovanni Scambia, Fabiola Moretti
Published 2019-09-01