Inhibition of Hedgehog Signaling in Fibroblasts, Pancreatic, and Lung Tumor Cells by Oxy186, an Oxysterol Analogue with Drug-Like Properties

by Feng Wang, Frank Stappenbeck, Farhad Parhami
Published 2019-05-01

Inhibition of Non-Small Cell Lung Cancer Cells by Oxy210, an Oxysterol-Derivative that Antagonizes TGFβ and Hedgehog Signaling

by Frank Stappenbeck, Feng Wang, Liu-Ya Tang, Ying E. Zhang, Farhad Parhami
Published 2019-10-01

Oxy210, a novel inhibitor of hedgehog and TGF‐β signalling, ameliorates hepatic fibrosis and hypercholesterolemia in mice

by Simon T. Hui, Feng Wang, Frank Stappenbeck, Samuel W. French, Clara E. Magyar, Farhad Parhami, Aldons J. Lusis
Published 2021-10-01

Identification of Anti-Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Oxysterol Derivatives In Vitro

by Hirofumi Ohashi, Feng Wang, Frank Stappenbeck, Kana Tsuchimoto, Chisa Kobayashi, Wakana Saso, Michiyo Kataoka, Masako Yamasaki, Kouji Kuramochi, Masamichi Muramatsu, Tadaki Suzuki, Camille Sureau, Makoto Takeda, Takaji Wakita, Farhad Parhami, Koichi Watashi
Published 2021-03-01