Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62

by Felicity E. Lumb, James Doonan, Kara S. Bell, Miguel A. Pineda, Marlene Corbet, Colin J. Suckling, Margaret M. Harnett, William Harnett
Published 2017-05-01

The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis

by James Doonan, Anuradha Tarafdar, Miguel A. Pineda, Felicity E. Lumb, Jenny Crowe, Aneesah M. Khan, Paul A. Hoskisson, Margaret M. Harnett, William Harnett
Published 2019-04-01

Protection Against Arthritis by the Parasitic Worm Product ES-62, and Its Drug-Like Small Molecule Analogues, Is Associated With Inhibition of Osteoclastogenesis

by James Doonan, Felicity E. Lumb, Miguel A. Pineda, Anuradha Tarafdar, Jenny Crowe, Aneesah M. Khan, Colin J. Suckling, Margaret M. Harnett, William Harnett
Published 2018-05-01

The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing.

by Jenny Crowe, Felicity E Lumb, James Doonan, Margaux Broussard, Anuradha Tarafdar, Miguel A Pineda, Carmen Landabaso, Lorna Mulvey, Paul A Hoskisson, Simon A Babayan, Colin Selman, William Harnett, Margaret M Harnett
Published 2020-03-01

Failure of the Anti-Inflammatory Parasitic Worm Product ES-62 to Provide Protection in Mouse Models of Type I Diabetes, Multiple Sclerosis, and Inflammatory Bowel Disease

by James Doonan, David Thomas, Michelle H. Wong, Hazel J. Ramage, Lamyaa Al-Riyami, Felicity E. Lumb, Kara S. Bell, Karen J. Fairlie-Clarke, Colin J. Suckling, Kathrin S. Michelsen, Hui-Rong Jiang, Anne Cooke, Margaret M. Harnett, William Harnett
Published 2018-10-01