Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate

by Ferdos Abid Ali, Ludovic Renault, Julian Gannon, Hailey L. Gahlon, Abhay Kotecha, Jin Chuan Zhou, David Rueda, Alessandro Costa
Published 2016-02-01

Cryo-EM structure of a licensed DNA replication origin

by Ferdos Abid Ali, Max E. Douglas, Julia Locke, Valerie E. Pye, Andrea Nans, John F. X. Diffley, Alessandro Costa
Published 2017-12-01

Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome

by Patrik Eickhoff, Hazal B. Kose, Fabrizio Martino, Tatjana Petojevic, Ferdos Abid Ali, Julia Locke, Nele Tamberg, Andrea Nans, James M. Berger, Michael R. Botchan, Hasan Yardimci, Alessandro Costa
Published 2019-09-01

Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome

by Panchali Goswami, Ferdos Abid Ali, Max E. Douglas, Julia Locke, Andrew Purkiss, Agnieszka Janska, Patrik Eickhoff, Anne Early, Andrea Nans, Alan M. C. Cheung, John F. X. Diffley, Alessandro Costa
Published 2018-11-01