Mitochondrial Protection by PARP Inhibition

by Ferenc Gallyas Jr, Balazs Sumegi
Published 2020-04-01

Role of Akt Activation in PARP Inhibitor Resistance in Cancer

by Ferenc Gallyas Jr, Balazs Sumegi, Csaba Szabo
Published 2020-02-01

Syntheses and Study of a Pyrroline Nitroxide Condensed Phospholene Oxide and a Pyrroline Nitroxide Attached Diphenylphosphine

by Mostafa Isbera, Balázs Bognár, Ferenc Gallyas, Attila Bényei, József Jekő, Tamás Kálai
Published 2021-07-01

Experimental Demyelination and Axonal Loss Are Reduced in MicroRNA-146a Deficient Mice

by Nellie A. Martin, Viktor Molnar, Gabor T. Szilagyi, Maria L. Elkjaer, Arkadiusz Nawrocki, Justyna Okarmus, Agnieszka Wlodarczyk, Eva K. Thygesen, Miklos Palkovits, Ferenc Gallyas, Ferenc Gallyas, Ferenc Gallyas, Martin R. Larsen, Hans Lassmann, Eirikur Benedikz, Trevor Owens, Asa F. Svenningsen, Zsolt Illes, Zsolt Illes, Zsolt Illes
Published 2018-03-01

Effect of Oxaliplatin, Olaparib and LY294002 in Combination on Triple-Negative Breast Cancer Cells

by Kitti Andreidesz, Balazs Koszegi, Dominika Kovacs, Viola Bagone Vantus, Ferenc Gallyas, Krisztina Kovacs
Published 2021-02-01

PARP Inhibitor PJ34 Protects Mitochondria and Induces DNA-Damage Mediated Apoptosis in Combination With Cisplatin or Temozolomide in B16F10 Melanoma Cells

by Anna Maria Cseh, Anna Maria Cseh, Zsolt Fabian, Ruben Quintana-Cabrera, Ruben Quintana-Cabrera, Ruben Quintana-Cabrera, Aliz Szabo, Aliz Szabo, Krisztian Eros, Krisztian Eros, Krisztian Eros, Maria Eugenia Soriano, Maria Eugenia Soriano, Ferenc Gallyas, Ferenc Gallyas, Ferenc Gallyas, Luca Scorrano, Luca Scorrano, Balazs Sumegi, Balazs Sumegi, Balazs Sumegi
Published 2019-05-01

PARP inhibition attenuates acute kidney allograft rejection by suppressing cell death pathways and activating PI-3K-Akt cascade.

by Karoly Kalmar-Nagy, Peter Degrell, Aliz Szabo, Katalin Sumegi, Istvan Wittmann, Ferenc Gallyas, Balazs Sumegi
Published 2013-01-01

Olaparib: A Clinically Applied PARP Inhibitor Protects from Experimental Crohn’s Disease and Maintains Barrier Integrity by Improving Bioenergetics through Rescuing Glycolysis in C...

by Dominika Kovács, Viola Bagóné Vántus, Eszter Vámos, Nikoletta Kálmán, Rudolf Schicho, Ferenc Gallyas, Balázs Radnai
Published 2021-01-01

BGP-15 Protects against Heart Failure by Enhanced Mitochondrial Biogenesis and Decreased Fibrotic Remodelling in Spontaneously Hypertensive Rats

by Orsolya Horvath, Katalin Ordog, Kitti Bruszt, Laszlo Deres, Ferenc Gallyas, Balazs Sumegi, Kalman Toth, Robert Halmosi
Published 2021-01-01

Involvement of Mitochondrial Mechanisms in the Cytostatic Effect of Desethylamiodarone in B16F10 Melanoma Cells

by Fadi H. J. Ramadan, Aliz Szabo, Dominika Kovacs, Aniko Takatsy, Rita Bognar, Ferenc Gallyas, Zita Bognar
Published 2020-10-01

Novel mechanisms of sildenafil in pulmonary hypertension involving cytokines/chemokines, MAP kinases and Akt.

by Tamas Kiss, Krisztina Kovacs, Andras Komocsi, Adrienn Tornyos, Petra Zalan, Balazs Sumegi, Ferenc Gallyas, Krisztina Kovacs
Published 2014-01-01

BGP-15 Protects against Oxidative Stress- or Lipopolysaccharide-Induced Mitochondrial Destabilization and Reduces Mitochondrial Production of Reactive Oxygen Species.

by Katalin Sumegi, Katalin Fekete, Csenge Antus, Balazs Debreceni, Eniko Hocsak, Ferenc Gallyas, Balazs Sumegi, Aliz Szabo
Published 2017-01-01

Antioxidant and anti-inflammatory effects in RAW264.7 macrophages of malvidin, a major red wine polyphenol.

by Eszter Bognar, Zsolt Sarszegi, Aliz Szabo, Balazs Debreceni, Nikoletta Kalman, Zsuzsanna Tucsek, Balazs Sumegi, Ferenc Gallyas
Published 2013-01-01

Modulation of Mitochondrial Quality Control Processes by BGP-15 in Oxidative Stress Scenarios: From Cell Culture to Heart Failure

by Orsolya Horvath, Katalin Ordog, Kitti Bruszt, Nikoletta Kalman, Dominika Kovacs, Balazs Radnai, Ferenc Gallyas, Kalman Toth, Robert Halmosi, Laszlo Deres
Published 2021-01-01

Amiodarone's major metabolite, desethylamiodarone inhibits proliferation of B16-F10 melanoma cells and limits lung metastasis formation in an in vivo experimental model.

by Zita Bognar, Anna Maria Cseh, Katalin Fekete, Csenge Antus, Rita Bognar, Antal Tapodi, Fadi H J Ramadan, Balazs Sumegi, Ferenc Gallyas
Published 2020-01-01

Chronic PARP-1 inhibition reduces carotid vessel remodeling and oxidative damage of the dorsal hippocampus in spontaneously hypertensive rats.

by Krisztian Eros, Klara Magyar, Laszlo Deres, Arpad Skazel, Adam Riba, Zoltan Vamos, Tamas Kalai, Ferenc Gallyas, Balazs Sumegi, Kalman Toth, Robert Halmosi
Published 2017-01-01

Desethylamiodarone-A metabolite of amiodarone-Induces apoptosis on T24 human bladder cancer cells via multiple pathways.

by Zita Bognar, Katalin Fekete, Csenge Antus, Eniko Hocsak, Rita Bognar, Antal Tapodi, Arpad Boronkai, Nelli Farkas, Ferenc Gallyas, Balazs Sumegi, Arpad Szanto
Published 2017-01-01

Thymic Atrophy and Apoptosis of CD4+CD8+ Thymocytes in the Cuprizone Model of Multiple Sclerosis.

by Izabella Solti, Krisztian Kvell, Gergely Talaber, Sara Veto, Peter Acs, Ferenc Gallyas, Zsolt Illes, Katalin Fekete, Petra Zalan, Arpad Szanto, Zita Bognar
Published 2015-01-01

Cytostatic Effect of a Novel Mitochondria-Targeted Pyrroline Nitroxide in Human Breast Cancer Lines

by Kitti Andreidesz, Aliz Szabo, Dominika Kovacs, Balazs Koszegi, Viola Bagone Vantus, Eszter Vamos, Mostafa Isbera, Tamas Kalai, Zita Bognar, Krisztina Kovacs, Ferenc Gallyas
Published 2021-08-01

Proteomic changes during experimental de- and remyelination in the corpus callosum.

by Gabor T Szilagyi, Arkadiusz M Nawrocki, Krisztian Eros, Janos Schmidt, Katalin Fekete, Maria L Elkjaer, Kirsten H Hyrlov, Martin R Larsen, Zsolt Illes, Ferenc Gallyas
Published 2020-01-01