Potentials and Pitfalls of Cross-Translational Models of Cognitive Impairment

by Noor Z. Al Dahhan, Fernanda G. De Felice, Fernanda G. De Felice, Fernanda G. De Felice, Douglas P. Munoz, Douglas P. Munoz
Published 2019-03-01

The Role of Leptin and Adiponectin in Obesity-Associated Cognitive Decline and Alzheimer’s Disease

by Leticia Forny-Germano, Fernanda G. De Felice, Fernanda G. De Felice, Marcelo Nunes do Nascimento Vieira
Published 2019-01-01

Behavioral Abnormalities in Knockout and Humanized Tau Mice

by Rafaella Araujo Gonçalves, Rafaella Araujo Gonçalves, Nadeeja Wijesekara, Paul E. Fraser, Paul E. Fraser, Fernanda G. De Felice, Fernanda G. De Felice, Fernanda G. De Felice
Published 2020-03-01

The Link Between Tau and Insulin Signaling: Implications for Alzheimer’s Disease and Other Tauopathies

by Rafaella Araujo Gonçalves, Rafaella Araujo Gonçalves, Nadeeja Wijesekara, Paul E. Fraser, Paul E. Fraser, Fernanda G. De Felice, Fernanda G. De Felice, Fernanda G. De Felice
Published 2019-02-01

Brain metabolic stress and neuroinflammation at the basis of cognitive impairment in Alzheimer’s disease

by Fernanda G. De Felice, Mychael V Lourenco
Published 2015-05-01

Challenges for Alzheimer's Disease Therapy: Insights from Novel Mechanisms Beyond Memory Defects

by Rudimar L. Frozza, Mychael V. Lourenco, Mychael V. Lourenco, Fernanda G. De Felice, Fernanda G. De Felice
Published 2018-02-01

Insulin Resistance as a Shared Pathogenic Mechanism Between Depression and Type 2 Diabetes

by Natalia de M. Lyra e Silva, Minh P. Lam, Claudio N. Soares, Claudio N. Soares, Douglas P. Munoz, Roumen Milev, Roumen Milev, Fernanda G. De Felice, Fernanda G. De Felice, Fernanda G. De Felice
Published 2019-02-01

Insulin Resistance in Alzheimer's Disease

by Laís S. S. Ferreira, Laís S. S. Ferreira, Caroline S. Fernandes, Caroline S. Fernandes, Marcelo N. N. Vieira, Marcelo N. N. Vieira, Fernanda G. De Felice, Fernanda G. De Felice
Published 2018-11-01

Soluble amyloid-b oligomers as synaptotoxins leading to cognitive impairment in Alzheimer’s disease

by Sergio T. Ferreira, Sergio T. Ferreira, Mychael V. Lourenco, Mauricio M. Oliveira, Fernanda G. De Felice
Published 2015-05-01

Interleukin-1β mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-β oligomers

by Andre F. Batista, Tayná Rody, Leticia Forny-Germano, Suzana Cerdeiro, Maria Bellio, Sergio T. Ferreira, Douglas P. Munoz, Fernanda G. De Felice
Published 2021-02-01

Amyloid-β triggers the release of neuronal hexokinase 1 from mitochondria.

by Leonardo M Saraiva, Gisele S Seixas da Silva, Antonio Galina, Wagner S da-Silva, William L Klein, Sérgio T Ferreira, Fernanda G De Felice
Published 2010-12-01

Long-term consequences of the absence of leptin signaling in early life

by Angela M Ramos-Lobo, Pryscila DS Teixeira, Isadora C Furigo, Helen M Melo, Natalia de M Lyra e Silva, Fernanda G De Felice, Jose Donato Jr
Published 2019-01-01

Cerebrospinal fluid irisin correlates with amyloid‐β, BDNF, and cognition in Alzheimer's disease

by Mychael V. Lourenco, Felipe C. Ribeiro, Felipe K. Sudo, Cláudia Drummond, Naima Assunção, Bart Vanderborght, Fernanda Tovar‐Moll, Paulo Mattos, Fernanda G. De Felice, Sergio T. Ferreira
Published 2020-01-01

The effect of lumbar puncture on the neurodegeneration biomarker neurofilament light in macaque monkeys

by Susan E. Boehnke, Emma L. Robertson, Brittney Armitage‐Brown, Robert G. Wither, Natalia M. Lyra e Silva, Andrew Winterborn, Ron Levy, Douglas J. Cook, Fernanda G. De Felice, Douglas P. Munoz
Published 2020-01-01

Extracellular vesicles derived from human Wharton’s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers...

by Victor Bodart-Santos, Luiza R. P. de Carvalho, Mariana A. de Godoy, André F. Batista, Leonardo M. Saraiva, Luize G. Lima, Carla Andreia Abreu, Fernanda G. De Felice, Antonio Galina, Rosalia Mendez-Otero, Sergio T. Ferreira
Published 2019-11-01

Palmitate Is Increased in the Cerebrospinal Fluid of Humans with Obesity and Induces Memory Impairment in Mice via Pro-inflammatory TNF-α

by Helen M. Melo, Gisele da S. Seixas da Silva, Marcella Ramos Sant’Ana, Camila Vieira Ligo Teixeira, Julia R. Clarke, Vivian S. Miya Coreixas, Bruno C. de Melo, Juliana T.S. Fortuna, Leticia Forny-Germano, José Henrique Ledo, Maíra S. Oliveira, Claudia P. Figueiredo, Raphaelle Pardossi-Piquard, Frédéric Checler, José María Delgado-García, Agnès Gruart, Licio A. Velloso, Marcio L.F. Balthazar, Dennys E. Cintra, Sergio T. Ferreira, Fernanda G. De Felice
Published 2020-02-01

Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice

by Claudia P. Figueiredo, Fernanda G. Q. Barros-Aragão, Rômulo L. S. Neris, Paula S. Frost, Carolina Soares, Isis N. O. Souza, Julianna D. Zeidler, Daniele C. Zamberlan, Virginia L. de Sousa, Amanda S. Souza, André Luis A. Guimarães, Maria Bellio, Jorge Marcondes de Souza, Soniza V. Alves-Leon, Gilda A. Neves, Heitor A. Paula-Neto, Newton G. Castro, Fernanda G. De Felice, Iranaia Assunção-Miranda, Julia R. Clarke, Andrea T. Da Poian, Sergio T. Ferreira
Published 2019-09-01

Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer’s disease

by Natalia M. Lyra e Silva, Rafaella A. Gonçalves, Tharick A. Pascoal, Ricardo A. S. Lima-Filho, Elisa de Paula França Resende, Erica L. M. Vieira, Antonio L. Teixeira, Leonardo C. de Souza, Julyanna A. Peny, Juliana T. S. Fortuna, Isadora C. Furigo, Debora Hashiguchi, Vivian S. Miya-Coreixas, Julia R. Clarke, Jose F. Abisambra, Beatriz M. Longo, Jose Donato, Paul E. Fraser, Pedro Rosa-Neto, Paulo Caramelli, Sergio T. Ferreira, Fernanda G. De Felice
Published 2021-04-01