Optimizing the Synthetic Route of Chromone-2-carboxylic Acids: A Step forward to Speed-up the Discovery of Chromone-based Multitarget-directed Ligands

by Fernando Cagide, Catarina Oliveira, Joana Reis, Fernanda Borges
Published 2019-11-01

The crystal structures of four N-(4-halophenyl)-4-oxo-4H-chromene-3-carboxamides

by Ligia R. Gomes, John Nicolson Low, Fernando Cagide, Fernanda Borges
Published 2015-01-01

Crystal structures of two 6-(2-hydroxybenzoyl)-5H-thiazolo[3,2-a]pyrimidin-5-ones

by Ligia R. Gomes, John Nicolson Low, Fernando Cagide, Fernanda Borges
Published 2015-07-01

Crystal structures of three 3,4,5-trimethoxybenzamide-based derivatives

by Ligia R. Gomes, John Nicolson Low, Catarina Oliveira, Fernando Cagide, Fernanda Borges
Published 2016-05-01

A comparison of the structures of some 2- and 3-substituted chromone derivatives: a structural study on the importance of the secondary carboxamide backbone for the inhibitory acti...

by Ligia R. Gomes, John Nicolson Low, Fernando Cagide, Alexandra Gaspar, Fernanda Borges
Published 2015-11-01

New insights in the discovery of novel h-MAO-B inhibitors: structural characterization of a series of N-phenyl-4-oxo-4H-chromene-3-carboxamide derivatives

by Ligia R. Gomes, John Nicolson Low, Fernando Cagide, Daniel Chavarria, Fernanda Borges
Published 2015-05-01

Surface Wiping Test to Study Biocide -Cinnamaldehyde Combination to Improve Efficiency in Surface Disinfection

by Joana F. Malheiro, Catarina Oliveira, Fernando Cagide, Fernanda Borges, Manuel Simões, Jean-Yves Maillard
Published 2020-10-01

Crystal structures of five 6-mercaptopurine derivatives

by Lígia R. Gomes, John Nicolson Low, Diogo Magalhães e Silva, Fernando Cagide, Fernanda Borges
Published 2016-03-01

Searching for new cytotoxic agents based on chromen-4-one and chromane-2,4-dione scaffolds

by Alexandra Gaspar, Maryam Mohabbati, Fernando Cagide, Nima Razzaghi-Asl, Ramin Miri, Omidreza Firuzi, Fernanda Borges
Published 2019-01-01

Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid

by José Teixeira, Catarina Oliveira, Fernando Cagide, Ricardo Amorim, Jorge Garrido, Fernanda Borges, Paulo J. Oliveira
Published 2018-01-01

A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients

by Cláudia M. Deus, Susana P. Pereira, Teresa Cunha-Oliveira, José Teixeira, Rui F. Simões, Fernando Cagide, Sofia Benfeito, Fernanda Borges, Nuno Raimundo, Paulo J. Oliveira
Published 2021-09-01

Boosting Drug Discovery for Parkinson’s: Enhancement of the Delivery of a Monoamine Oxidase-B Inhibitor by Brain-Targeted PEGylated Polycaprolactone-Based Nanoparticles

by Miguel Pinto, Carlos Fernandes, Eva Martins, Renata Silva, Sofia Benfeito, Fernando Cagide, Ricardo F. Mendes, Filipe A. Almeida Paz, Jorge Garrido, Fernando Remião, Fernanda Borges
Published 2019-07-01

Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondria

by José Teixeira, Catarina Oliveira, Ricardo Amorim, Fernando Cagide, Jorge Garrido, José A. Ribeiro, Carlos M. Pereira, António F. Silva, Paula B. Andrade, Paulo J. Oliveira, Fernanda Borges
Published 2017-07-01

Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases

by Daniel Chavarria, Ophelie Da Silva, Sofia Benfeito, Sandra Barreiro, Jorge Garrido, Fernando Cagide, Pedro Soares, Fernando Remião, Xavier Brazzolotto, Florian Nachon, Paulo J. Oliveira, José Dias, Fernanda Borges
Published 2021-02-01

Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors

by Catarina Oliveira, Fernando Cagide, José Teixeira, José Teixeira, Ricardo Amorim, Ricardo Amorim, Lisa Sequeira, Francesco Mesiti, Tiago Silva, Tiago Silva, Jorge Garrido, Jorge Garrido, Fernando Remião, Santiago Vilar, Eugenio Uriarte, Eugenio Uriarte, Paulo J. Oliveira, Fernanda Borges
Published 2018-04-01